The Role of Active Site Residues in ATP Binding and Catalysis in the Methanosarcina thermophila Acetate Kinase

Acetate kinase (ACK), which catalyzes the reversible phosphorylation of acetate by ATP, is a member of the acetate and sugar kinase/heat shock cognate/actin (ASKHA) superfamily. ASKHA family members share a common core fold that includes an ATPase domain with five structural motifs. The PHOSPHATE1 m...

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Bibliographic Details
Main Authors: Cheryl Ingram-Smith, Jeffrey Wharton, Christian Reinholz, Tara Doucet, Rachel Hesler, Kerry Smith
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Life
Subjects:
Online Access:http://www.mdpi.com/2075-1729/5/1/861