Epigallocatechin gallate: a review
Epigallocatechin gallate is the major component of the polyphenolic fraction of green tea and is responsible for most of the therapeutic benefits of green tea consumption. A number of preclinical in vivo and in vitro experiments as well as clinical trials have shown a wide range of biological and ph...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2018-10-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-201810-0001_epigallocatechin-gallate-a-review.php |
| _version_ | 1797897497591414784 |
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| author | L. Bartosikova J. Necas |
| author_facet | L. Bartosikova J. Necas |
| author_sort | L. Bartosikova |
| collection | DOAJ |
| description | Epigallocatechin gallate is the major component of the polyphenolic fraction of green tea and is responsible for most of the therapeutic benefits of green tea consumption. A number of preclinical in vivo and in vitro experiments as well as clinical trials have shown a wide range of biological and pharmacological properties of polyphenolic compounds such as anti-oxidative, antimicrobial, anti-allergic, anti-diabetic, anti-inflammatory, anti-cancer, chemoprotective, neuroprotective and immunomodulatory effects. Epigallocatechin gallate controls high blood pressure, decreases blood cholesterol and body fat and decreases the risk of osteoporotic fractures. Further research should be performed to monitor the pharmacological and clinical effects of green tea and to more clearly elucidate its mechanisms of action and the potential for its use in medicine. |
| first_indexed | 2024-04-10T07:58:16Z |
| format | Article |
| id | doaj.art-29587a1657d744c9b29fa2b3f2be51b2 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T07:58:16Z |
| publishDate | 2018-10-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-29587a1657d744c9b29fa2b3f2be51b22023-02-23T03:50:47ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922018-10-01631044346710.17221/31/2018-VETMEDvet-201810-0001Epigallocatechin gallate: a reviewL. BartosikovaJ. Necas0Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech RepublicEpigallocatechin gallate is the major component of the polyphenolic fraction of green tea and is responsible for most of the therapeutic benefits of green tea consumption. A number of preclinical in vivo and in vitro experiments as well as clinical trials have shown a wide range of biological and pharmacological properties of polyphenolic compounds such as anti-oxidative, antimicrobial, anti-allergic, anti-diabetic, anti-inflammatory, anti-cancer, chemoprotective, neuroprotective and immunomodulatory effects. Epigallocatechin gallate controls high blood pressure, decreases blood cholesterol and body fat and decreases the risk of osteoporotic fractures. Further research should be performed to monitor the pharmacological and clinical effects of green tea and to more clearly elucidate its mechanisms of action and the potential for its use in medicine.https://vetmed.agriculturejournals.cz/artkey/vet-201810-0001_epigallocatechin-gallate-a-review.phpepigallocatechin-3-o-gallatepharmacokineticstoxicitybiological activity |
| spellingShingle | L. Bartosikova J. Necas Epigallocatechin gallate: a review Veterinární Medicína epigallocatechin-3-o-gallate pharmacokinetics toxicity biological activity |
| title | Epigallocatechin gallate: a review |
| title_full | Epigallocatechin gallate: a review |
| title_fullStr | Epigallocatechin gallate: a review |
| title_full_unstemmed | Epigallocatechin gallate: a review |
| title_short | Epigallocatechin gallate: a review |
| title_sort | epigallocatechin gallate a review |
| topic | epigallocatechin-3-o-gallate pharmacokinetics toxicity biological activity |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-201810-0001_epigallocatechin-gallate-a-review.php |
| work_keys_str_mv | AT lbartosikova epigallocatechingallateareview AT jnecas epigallocatechingallateareview |