H3K18Ac as a Marker of Cancer Progression and Potential Target of Anti-Cancer Therapy

H3K18Ac as a Marker of Cancer Progression and Potential Target of Anti-Cancer Therapy

Acetylation and deacetylation are posttranslational modifications (PTMs) which affect the regulation of chromatin structure and its remodeling. Acetylation of histone 3 at lysine placed on position 18 (H3K18Ac) plays an important role in driving progression of many types of cancer, including breast,...

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Bibliographic Details
Main Authors: Marta Hałasa, Anna Wawruszak, Alicja Przybyszewska, Anna Jaruga, Małgorzata Guz, Joanna Kałafut, Andrzej Stepulak, Marek Cybulski
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
histone acetylation
histone deacetylation
HATs
HDACs
H3K18Ac
cancer hallmarks
Online Access:https://www.mdpi.com/2073-4409/8/5/485

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