Arylamine Analogs of Methylene Blue: Substituent Effect on Aggregation Behavior and DNA Binding

Arylamine Analogs of Methylene Blue: Substituent Effect on Aggregation Behavior and DNA Binding

The synthesis of new phenothiazine derivatives, analogs of Methylene Blue, is of particular interest in the design of new drugs, as well as in the development of a new generation of agents for photodynamic therapy. In this study, two new derivatives of phenothiazine, i.e., 3,7-bis(4-aminophenylamino...

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Bibliographic Details
Main Authors: Alena Khadieva, Olga Mostovaya, Pavel Padnya, Valeriy Kalinin, Denis Grishaev, Dmitrii Tumakov, Ivan Stoikov
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
methylene blue
phenothiazine
3,7-bis(N-phenylamino)phenothiazin-5-iums
DNA
intercalation
dimerization
Online Access:https://www.mdpi.com/1422-0067/22/11/5847

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