The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells

The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells

Abstract Background In rodents, research has revealed a role of liver X receptors (LXR) in controlling lipid homeostasis and regulating the synthesis of polyunsaturated fatty acids (PUFA). Recent data suggest that LXRB is the predominant LXR subtype in ruminant mammary cells, but its role in lipid m...

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Bibliographic Details
Main Authors: Wenying Zhang, Changhui Zhang, Jun Luo, Huifen Xu, Jianxin Liu, Juan J. Loor, Hengbo Shi
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Elongase
Lipid homeostasis
Liver X receptor, Mammary gland
Polyunsaturated fatty acids
Online Access:https://doi.org/10.1186/s40104-022-00774-4

Internet

https://doi.org/10.1186/s40104-022-00774-4

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