Quality of Life after Frey’s Procedure in Patients with Chronic Pancreatitis
Introduction: Chronic pancreatitis is a debilitating disease, associated with excruciating abdominal pain, exocrine and endocrine pancreatic insufficiency. Different types of surgical techniques have been described for the management of complications of this disease. The most common procedure w...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-03-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7417/16736_CE[Ra]_F(Sh)_PF1(AYAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Introduction: Chronic pancreatitis is a debilitating disease,
associated with excruciating abdominal pain, exocrine and
endocrine pancreatic insufficiency. Different types of surgical
techniques have been described for the management of
complications of this disease. The most common procedure
which has been adopted for improving the quality of life of the
patients with chronic pancreatitis is Frey’s Procedure. It is an
organ preserving procedure in which the main pancreatic duct
is drained by lateral pancreatico-jejunostomy along with coring
of the head of the pancreas.
Aim: In this study, we have assessed the outcome of Frey’s
procedure in terms of quality of life in patients with chronic
pancreatitis.
Materials and Methods: This was a prospective observational
study done at a tertiary care center in West Bengal, India. The
study period was from 2010 to 2014. All the patients who have
undergone Frey’s Procedure during the study duration and with
the postoperative histopathology of chronic pancreatitis were
included in this study. The preoperative and postoperative pain
and quality of life assessment was done using VAS score (0-100)
and EORTC QLQ-C30 (Version 3) respectively. The statistical
analysis was performed with the help of Epi Info (TM) 3.5.3.
Results: A total of 35 patients with chronic pancreatitis
underwent Frey’s procedure during the study period. The
mean age (mean ± s.e) of the 33 patients included in the study
was 38.48±5.55 years with a range of 29-49 years. The mean
preoperative Physical Functional Domain (PFD), Physical
Domain (PD), Emotional Domain (ED), Social Domain (SD) and
general health raw score with standard errors were 32.06±0.40,
37.86±0.36, 15.18±0.32, 8.63±0.31 and 4.48±0.26 respectively.
ANOVA showed that there was significant differences in PFD,
PD, ED, SD and GH values during different time period of follow
up (p<0.0001) and as per Critical Difference the postoperative
values of PFD, PD, ED and SD decreased while postoperative
value of GH increased significantly in different months compared
to the preoperative values.
Conclusion: We conclude that Frey’s procedure is a low risk
surgery, which significantly improves the quality of life of the
patients with chronic pancreatitis in all the domains and can be
recommended as a surgical therapy for such patients. |
|---|---|
| ISSN: | 2249-782X 0973-709X |