COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series.
The management of respiratory failure during the present pandemic has been a challenging issue for the intensivists. There have been few case series and case reports on myasthenic crisis precipitated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The combination of corona...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Towarzystwo Pomocy Doraźnej
2021-09-01
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| Series: | Critical Care Innovations |
| Subjects: | |
| Online Access: | https://www.irdim.net/cci/4(3)27-32.html |
| Summary: | The management of respiratory failure during the present pandemic has been a challenging issue for the intensivists. There have been few case series and case reports on myasthenic crisis precipitated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The combination of coronavirus disease-19 (COVID-19) pneumonia and myasthenic crisis can result in increased morbidity and mortality if not managed efficiently. The choice of ventilation ranges from non-invasive to invasive. However a lack of proper understanding of pathophysiology of myasthenia gravis and also the COVID-19 could make the decision of selecting the modality of ventilation a real difficult one. Although invasive ventilation is traditionally indicated when the myasthenia gravis patient presents in myasthenic crisis, there is emerging evidence for use of non-invasive ventilation with BiPAP mode in these patients. We present two cases of myasthenic crisis precipitated by SARS-CoV-2 which were successfully managed on non-invasive ventilation, thereby avoiding intubation and complications of invasive mechanical ventilation. |
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| ISSN: | 2545-2533 |