COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series.
The management of respiratory failure during the present pandemic has been a challenging issue for the intensivists. There have been few case series and case reports on myasthenic crisis precipitated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The combination of corona...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Towarzystwo Pomocy Doraźnej
2021-09-01
|
| Series: | Critical Care Innovations |
| Subjects: | |
| Online Access: | https://www.irdim.net/cci/4(3)27-32.html |
| _version_ | 1819124931180363776 |
|---|---|
| author | Mohd Mustahsin Sanjay Choubey Varun Malhotra |
| author_facet | Mohd Mustahsin Sanjay Choubey Varun Malhotra |
| author_sort | Mohd Mustahsin |
| collection | DOAJ |
| description | The management of respiratory failure during the present pandemic has been a challenging issue for the intensivists. There have been few case series and case reports on myasthenic crisis precipitated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The combination of coronavirus disease-19 (COVID-19) pneumonia and myasthenic crisis can result in increased morbidity and mortality if not managed efficiently. The choice of ventilation ranges from non-invasive to invasive. However a lack of proper understanding of pathophysiology of myasthenia gravis and also the COVID-19 could make the decision of selecting the modality of ventilation a real difficult one. Although invasive ventilation is traditionally indicated when the myasthenia gravis patient presents in myasthenic crisis, there is emerging evidence for use of non-invasive ventilation with BiPAP mode in these patients. We present two cases of myasthenic crisis precipitated by SARS-CoV-2 which were successfully managed on non-invasive ventilation, thereby avoiding intubation and complications of invasive mechanical ventilation. |
| first_indexed | 2024-12-22T07:32:05Z |
| format | Article |
| id | doaj.art-2967a223564c41569d231a7a38ecf8bb |
| institution | Directory Open Access Journal |
| issn | 2545-2533 |
| language | English |
| last_indexed | 2024-12-22T07:32:05Z |
| publishDate | 2021-09-01 |
| publisher | Towarzystwo Pomocy Doraźnej |
| record_format | Article |
| series | Critical Care Innovations |
| spelling | doaj.art-2967a223564c41569d231a7a38ecf8bb2022-12-21T18:33:59ZengTowarzystwo Pomocy DoraźnejCritical Care Innovations2545-25332021-09-0143273210.32114/CCI.2021.4.3.27.32COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series.Mohd Mustahsin0https://orcid.org/0000-0003-2503-1906Sanjay Choubey1https://orcid.org/0000-0001-6052-0647Varun Malhotra2https://orcid.org/0000-0002-1940-1168Department of Anesthesiology and Critical Care, Era’s Lucknow Medical College and Hospital, Lucknow, India.Department of Anesthesiology and Critical Care, Era’s Lucknow Medical College and Hospital, Lucknow, India. Department of Medicine, Era’s Lucknow Medical College and Hospital, Lucknow, India.The management of respiratory failure during the present pandemic has been a challenging issue for the intensivists. There have been few case series and case reports on myasthenic crisis precipitated by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The combination of coronavirus disease-19 (COVID-19) pneumonia and myasthenic crisis can result in increased morbidity and mortality if not managed efficiently. The choice of ventilation ranges from non-invasive to invasive. However a lack of proper understanding of pathophysiology of myasthenia gravis and also the COVID-19 could make the decision of selecting the modality of ventilation a real difficult one. Although invasive ventilation is traditionally indicated when the myasthenia gravis patient presents in myasthenic crisis, there is emerging evidence for use of non-invasive ventilation with BiPAP mode in these patients. We present two cases of myasthenic crisis precipitated by SARS-CoV-2 which were successfully managed on non-invasive ventilation, thereby avoiding intubation and complications of invasive mechanical ventilation.https://www.irdim.net/cci/4(3)27-32.htmlmyasthenic crisiscovid-19noninvasive ventilationnivcase report |
| spellingShingle | Mohd Mustahsin Sanjay Choubey Varun Malhotra COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. Critical Care Innovations myasthenic crisis covid-19 noninvasive ventilation niv case report |
| title | COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. |
| title_full | COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. |
| title_fullStr | COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. |
| title_full_unstemmed | COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. |
| title_short | COVID-19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation: a case series. |
| title_sort | covid 19 patients in myasthenic crisis managed successfully with noninvasive positive pressure ventilation a case series |
| topic | myasthenic crisis covid-19 noninvasive ventilation niv case report |
| url | https://www.irdim.net/cci/4(3)27-32.html |
| work_keys_str_mv | AT mohdmustahsin covid19patientsinmyastheniccrisismanagedsuccessfullywithnoninvasivepositivepressureventilationacaseseries AT sanjaychoubey covid19patientsinmyastheniccrisismanagedsuccessfullywithnoninvasivepositivepressureventilationacaseseries AT varunmalhotra covid19patientsinmyastheniccrisismanagedsuccessfullywithnoninvasivepositivepressureventilationacaseseries |