Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea
Background and aim: Pyrrolizidine alkaloids (PAs) are secondary metabolites produced by plants. At present, more than 660 PAs have been identified in more than 6000 plants, mainly belonging to the families Boraginaceae, Compositae, Leguminosae, and so forth. PAs and their corresponding nitrogen oxid...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Pharmacological Research - Modern Chinese Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142523000635 |
| _version_ | 1797682789564284928 |
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| author | Ke Zan Zhao Wang Ying Wang Jian-Dong Yu Hong-Yu Jin Shuang-Cheng Ma |
| author_facet | Ke Zan Zhao Wang Ying Wang Jian-Dong Yu Hong-Yu Jin Shuang-Cheng Ma |
| author_sort | Ke Zan |
| collection | DOAJ |
| description | Background and aim: Pyrrolizidine alkaloids (PAs) are secondary metabolites produced by plants. At present, more than 660 PAs have been identified in more than 6000 plants, mainly belonging to the families Boraginaceae, Compositae, Leguminosae, and so forth. PAs and their corresponding nitrogen oxides have variedtoxicities, including hepatotoxicity, pulmonary toxicity, and genotoxicity. The long-term intake of PAs can lead to cancer. This study aimed to review the literature on tea derived from C. sinensis only. Results: Tea is one of the most frequently items usedas both medicine and food. In recent years, PAs have been frequently detected in tea. The tea plant itself does not produce PAs, theymainly come from soil contamination caused by weeds in the tea garden. Conclusions: This study reviewed data published in recent years on the distribution, detection, risk assessment, strategy, and prospects of PAs in tea. The findings of this study mightfacilitate the qualityimprovementand safe use of PAs in tea. |
| first_indexed | 2024-03-12T00:04:54Z |
| format | Article |
| id | doaj.art-2967bc13303e48a48bbabfb1fcb2345f |
| institution | Directory Open Access Journal |
| issn | 2667-1425 |
| language | English |
| last_indexed | 2024-03-12T00:04:54Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research - Modern Chinese Medicine |
| spelling | doaj.art-2967bc13303e48a48bbabfb1fcb2345f2023-09-17T04:57:55ZengElsevierPharmacological Research - Modern Chinese Medicine2667-14252023-09-018100277Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in teaKe Zan0Zhao Wang1Ying Wang2Jian-Dong Yu3Hong-Yu Jin4Shuang-Cheng Ma5National Institutes for Food and Drug Control, Beijing 102629, ChinaNational Institutes for Food and Drug Control, Beijing 102629, ChinaNational Institutes for Food and Drug Control, Beijing 102629, ChinaNational Institutes for Food and Drug Control, Beijing 102629, ChinaCorresponding authors at: National Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing 102629, China.; National Institutes for Food and Drug Control, Beijing 102629, ChinaCorresponding authors at: National Institutes for Food and Drug Control, No. 31 Huatuo Road, Daxing District, Beijing 102629, China.; National Institutes for Food and Drug Control, Beijing 102629, ChinaBackground and aim: Pyrrolizidine alkaloids (PAs) are secondary metabolites produced by plants. At present, more than 660 PAs have been identified in more than 6000 plants, mainly belonging to the families Boraginaceae, Compositae, Leguminosae, and so forth. PAs and their corresponding nitrogen oxides have variedtoxicities, including hepatotoxicity, pulmonary toxicity, and genotoxicity. The long-term intake of PAs can lead to cancer. This study aimed to review the literature on tea derived from C. sinensis only. Results: Tea is one of the most frequently items usedas both medicine and food. In recent years, PAs have been frequently detected in tea. The tea plant itself does not produce PAs, theymainly come from soil contamination caused by weeds in the tea garden. Conclusions: This study reviewed data published in recent years on the distribution, detection, risk assessment, strategy, and prospects of PAs in tea. The findings of this study mightfacilitate the qualityimprovementand safe use of PAs in tea.http://www.sciencedirect.com/science/article/pii/S2667142523000635Content determinationExogenous contaminationPyrrolizidine alkaloidsRisk assessmentTea |
| spellingShingle | Ke Zan Zhao Wang Ying Wang Jian-Dong Yu Hong-Yu Jin Shuang-Cheng Ma Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea Pharmacological Research - Modern Chinese Medicine Content determination Exogenous contamination Pyrrolizidine alkaloids Risk assessment Tea |
| title | Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea |
| title_full | Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea |
| title_fullStr | Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea |
| title_full_unstemmed | Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea |
| title_short | Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea |
| title_sort | distribution determination method risk assessment and strategy of exogenous pyrrolizidine alkaloids in tea |
| topic | Content determination Exogenous contamination Pyrrolizidine alkaloids Risk assessment Tea |
| url | http://www.sciencedirect.com/science/article/pii/S2667142523000635 |
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