Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults
Based on neurofeedback (NF) training as a neurocognitive treatment in attention-deficit/hyperactivity disorder (ADHD), we designed a randomized, controlled functional near-infrared spectroscopy (fNIRS) NF intervention embedded in an immersive virtual reality classroom in which participants learned t...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-09-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00425/full |
| _version_ | 1818271352863326208 |
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| author | Justin Hudak Friederike Blume Thomas Dresler Thomas Dresler Florian B. Haeussinger Tobias J. Renner Andreas J. Fallgatter Andreas J. Fallgatter Andreas J. Fallgatter Caterina Gawrilow Caterina Gawrilow Caterina Gawrilow Ann-Christine Ehlis Ann-Christine Ehlis |
| author_facet | Justin Hudak Friederike Blume Thomas Dresler Thomas Dresler Florian B. Haeussinger Tobias J. Renner Andreas J. Fallgatter Andreas J. Fallgatter Andreas J. Fallgatter Caterina Gawrilow Caterina Gawrilow Caterina Gawrilow Ann-Christine Ehlis Ann-Christine Ehlis |
| author_sort | Justin Hudak |
| collection | DOAJ |
| description | Based on neurofeedback (NF) training as a neurocognitive treatment in attention-deficit/hyperactivity disorder (ADHD), we designed a randomized, controlled functional near-infrared spectroscopy (fNIRS) NF intervention embedded in an immersive virtual reality classroom in which participants learned to control overhead lighting with their dorsolateral prefrontal brain activation. We tested the efficacy of the intervention on healthy adults displaying high impulsivity as a sub-clinical population sharing common features with ADHD. Twenty participants, 10 in an experimental and 10 in a shoulder muscle-based electromyography control group, underwent eight training sessions across 2 weeks. Training was bookended by a pre- and post-test including go/no-go, n-back, and stop-signal tasks (SST). Results indicated a significant reduction in commission errors on the no-go task with a simultaneous increase in prefrontal oxygenated hemoglobin concentration for the experimental group, but not for the control group. Furthermore, the ability of the subjects to gain control over the feedback parameter correlated strongly with the reduction in commission errors for the experimental, but not for the control group, indicating the potential importance of learning feedback control in moderating behavioral outcomes. In addition, participants of the fNIRS group showed a reduction in reaction time variability on the SST. Results indicate a clear effect of our NF intervention in reducing impulsive behavior possibly via a strengthening of frontal lobe functioning. Virtual reality additions to conventional NF may be one way to improve the ecological validity and symptom-relevance of the training situation, hence positively affecting transfer of acquired skills to real life. |
| first_indexed | 2024-12-12T21:24:49Z |
| format | Article |
| id | doaj.art-29686db6146245f792cb2e16d40a90f7 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-12T21:24:49Z |
| publishDate | 2017-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-29686db6146245f792cb2e16d40a90f72022-12-22T00:11:28ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612017-09-011110.3389/fnhum.2017.00425280311Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive AdultsJustin Hudak0Friederike Blume1Thomas Dresler2Thomas Dresler3Florian B. Haeussinger4Tobias J. Renner5Andreas J. Fallgatter6Andreas J. Fallgatter7Andreas J. Fallgatter8Caterina Gawrilow9Caterina Gawrilow10Caterina Gawrilow11Ann-Christine Ehlis12Ann-Christine Ehlis13LEAD Graduate School & Research Network, University of TübingenTübingen, GermanyLEAD Graduate School & Research Network, University of TübingenTübingen, GermanyLEAD Graduate School & Research Network, University of TübingenTübingen, GermanyDepartment of Psychiatry and Psychotherapy, University Hospital TübingenTübingen, GermanyDepartment of Psychiatry and Psychotherapy, University Hospital TübingenTübingen, GermanyDepartment of Child and Adolescence Psychiatry, University Hospital TübingenTübingen, GermanyLEAD Graduate School & Research Network, University of TübingenTübingen, GermanyDepartment of Psychiatry and Psychotherapy, University Hospital TübingenTübingen, GermanyCenter for Integrative Neuroscience, University of TübingenTübingen, GermanyLEAD Graduate School & Research Network, University of TübingenTübingen, GermanyDepartment of Psychology, University of TübingenTübingen, GermanyCenter for Individual Development and Adaptive Education of Children at Risk, Goethe University FrankfurtFrankfurt, GermanyLEAD Graduate School & Research Network, University of TübingenTübingen, GermanyDepartment of Psychiatry and Psychotherapy, University Hospital TübingenTübingen, GermanyBased on neurofeedback (NF) training as a neurocognitive treatment in attention-deficit/hyperactivity disorder (ADHD), we designed a randomized, controlled functional near-infrared spectroscopy (fNIRS) NF intervention embedded in an immersive virtual reality classroom in which participants learned to control overhead lighting with their dorsolateral prefrontal brain activation. We tested the efficacy of the intervention on healthy adults displaying high impulsivity as a sub-clinical population sharing common features with ADHD. Twenty participants, 10 in an experimental and 10 in a shoulder muscle-based electromyography control group, underwent eight training sessions across 2 weeks. Training was bookended by a pre- and post-test including go/no-go, n-back, and stop-signal tasks (SST). Results indicated a significant reduction in commission errors on the no-go task with a simultaneous increase in prefrontal oxygenated hemoglobin concentration for the experimental group, but not for the control group. Furthermore, the ability of the subjects to gain control over the feedback parameter correlated strongly with the reduction in commission errors for the experimental, but not for the control group, indicating the potential importance of learning feedback control in moderating behavioral outcomes. In addition, participants of the fNIRS group showed a reduction in reaction time variability on the SST. Results indicate a clear effect of our NF intervention in reducing impulsive behavior possibly via a strengthening of frontal lobe functioning. Virtual reality additions to conventional NF may be one way to improve the ecological validity and symptom-relevance of the training situation, hence positively affecting transfer of acquired skills to real life.http://journal.frontiersin.org/article/10.3389/fnhum.2017.00425/fullNIRSneurofeedbackvirtual realityimpulsivityADHD |
| spellingShingle | Justin Hudak Friederike Blume Thomas Dresler Thomas Dresler Florian B. Haeussinger Tobias J. Renner Andreas J. Fallgatter Andreas J. Fallgatter Andreas J. Fallgatter Caterina Gawrilow Caterina Gawrilow Caterina Gawrilow Ann-Christine Ehlis Ann-Christine Ehlis Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults Frontiers in Human Neuroscience NIRS neurofeedback virtual reality impulsivity ADHD |
| title | Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults |
| title_full | Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults |
| title_fullStr | Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults |
| title_full_unstemmed | Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults |
| title_short | Near-Infrared Spectroscopy-Based Frontal Lobe Neurofeedback Integrated in Virtual Reality Modulates Brain and Behavior in Highly Impulsive Adults |
| title_sort | near infrared spectroscopy based frontal lobe neurofeedback integrated in virtual reality modulates brain and behavior in highly impulsive adults |
| topic | NIRS neurofeedback virtual reality impulsivity ADHD |
| url | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00425/full |
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