Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accum...

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Bibliographic Details
Main Authors: Valerie Hox, Evelijn Lourijsen, Arnout Jordens, Kristian Aasbjerg, Ioana Agache, Isam Alobid, Claus Bachert, Koen Boussery, Paloma Campo, Wytske Fokkens, Peter Hellings, Claire Hopkins, Ludger Klimek, Mika Mäkelä, Ralph Mösges, Joaquim Mullol, Laura Pujols, Carmen Rondon, Michael Rudenko, Sanna Toppila-Salmi, Glenis Scadding, Sophie Scheire, Peter-Valentin Tomazic, Thibaut Van Zele, Martin Wagemann, Job F. M. van Boven, Philippe Gevaert
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical and Translational Allergy
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Online Access:http://link.springer.com/article/10.1186/s13601-019-0303-6
Description
Summary:Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.
ISSN:2045-7022