Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper
Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accum...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Clinical and Translational Allergy |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13601-019-0303-6 |
| _version_ | 1818731597589905408 |
|---|---|
| author | Valerie Hox Evelijn Lourijsen Arnout Jordens Kristian Aasbjerg Ioana Agache Isam Alobid Claus Bachert Koen Boussery Paloma Campo Wytske Fokkens Peter Hellings Claire Hopkins Ludger Klimek Mika Mäkelä Ralph Mösges Joaquim Mullol Laura Pujols Carmen Rondon Michael Rudenko Sanna Toppila-Salmi Glenis Scadding Sophie Scheire Peter-Valentin Tomazic Thibaut Van Zele Martin Wagemann Job F. M. van Boven Philippe Gevaert |
| author_facet | Valerie Hox Evelijn Lourijsen Arnout Jordens Kristian Aasbjerg Ioana Agache Isam Alobid Claus Bachert Koen Boussery Paloma Campo Wytske Fokkens Peter Hellings Claire Hopkins Ludger Klimek Mika Mäkelä Ralph Mösges Joaquim Mullol Laura Pujols Carmen Rondon Michael Rudenko Sanna Toppila-Salmi Glenis Scadding Sophie Scheire Peter-Valentin Tomazic Thibaut Van Zele Martin Wagemann Job F. M. van Boven Philippe Gevaert |
| author_sort | Valerie Hox |
| collection | DOAJ |
| description | Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease. |
| first_indexed | 2024-12-17T23:20:13Z |
| format | Article |
| id | doaj.art-296b770c3ab747efa46fdc47d2797d1c |
| institution | Directory Open Access Journal |
| issn | 2045-7022 |
| language | English |
| last_indexed | 2024-12-17T23:20:13Z |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Allergy |
| spelling | doaj.art-296b770c3ab747efa46fdc47d2797d1c2022-12-21T21:28:55ZengWileyClinical and Translational Allergy2045-70222020-01-0110112710.1186/s13601-019-0303-6Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paperValerie Hox0Evelijn Lourijsen1Arnout Jordens2Kristian Aasbjerg3Ioana Agache4Isam Alobid5Claus Bachert6Koen Boussery7Paloma Campo8Wytske Fokkens9Peter Hellings10Claire Hopkins11Ludger Klimek12Mika Mäkelä13Ralph Mösges14Joaquim Mullol15Laura Pujols16Carmen Rondon17Michael Rudenko18Sanna Toppila-Salmi19Glenis Scadding20Sophie Scheire21Peter-Valentin Tomazic22Thibaut Van Zele23Martin Wagemann24Job F. M. van Boven25Philippe Gevaert26Cliniques Universitaires Saint-Luc BrusselsDepartment of Otorhinolaryngology, Amsterdam University Medical Centres, AMCUpper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University HospitalBispebjerg University HospitalFaculty of Medicine, Transsylvania UniversityHospital Clínic, IDIBAPS, CEBERES Universitat de BarcelonaUpper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University HospitalPharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent UniversityAllergy Unit, Hospital Regional Universitario of Málaga, IBIMA, ARADyALDepartment of Otorhinolaryngology, Amsterdam University Medical Centres, AMCDepartment of Ear, Nose and Throat Disease, University HospitalsENT Department, Guy’s & St Thomas’ HospitalCenter of Rhinology and AllergologySkin and Allergy Hospital, Helsinki University Hospital and University of HelsinkiUniversity of CologneHospital Clínic, IDIBAPS, CEBERES Universitat de BarcelonaHospital Clínic, IDIBAPS, CEBERES Universitat de BarcelonaAllergy Unit, Hospital Regional Universitario of Málaga, IBIMA, ARADyALLondon Allergy and Immunology CenterSkin and Allergy Hospital, Helsinki University Hospital and University of HelsinkiRoyal National Throat, Nose and Ear HospitalPharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent UniversityMedical University GrazUpper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University HospitalHeinrich-Heine-UniversityDepartment of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), University of GroningenUpper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University HospitalAbstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.http://link.springer.com/article/10.1186/s13601-019-0303-6GlucocorticosteroidsRhinitisRhinosinusitis |
| spellingShingle | Valerie Hox Evelijn Lourijsen Arnout Jordens Kristian Aasbjerg Ioana Agache Isam Alobid Claus Bachert Koen Boussery Paloma Campo Wytske Fokkens Peter Hellings Claire Hopkins Ludger Klimek Mika Mäkelä Ralph Mösges Joaquim Mullol Laura Pujols Carmen Rondon Michael Rudenko Sanna Toppila-Salmi Glenis Scadding Sophie Scheire Peter-Valentin Tomazic Thibaut Van Zele Martin Wagemann Job F. M. van Boven Philippe Gevaert Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper Clinical and Translational Allergy Glucocorticosteroids Rhinitis Rhinosinusitis |
| title | Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper |
| title_full | Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper |
| title_fullStr | Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper |
| title_full_unstemmed | Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper |
| title_short | Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper |
| title_sort | benefits and harm of systemic steroids for short and long term use in rhinitis and rhinosinusitis an eaaci position paper |
| topic | Glucocorticosteroids Rhinitis Rhinosinusitis |
| url | http://link.springer.com/article/10.1186/s13601-019-0303-6 |
| work_keys_str_mv | AT valeriehox benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT evelijnlourijsen benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT arnoutjordens benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT kristianaasbjerg benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT ioanaagache benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT isamalobid benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT clausbachert benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT koenboussery benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT palomacampo benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT wytskefokkens benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT peterhellings benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT clairehopkins benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT ludgerklimek benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT mikamakela benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT ralphmosges benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT joaquimmullol benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT laurapujols benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT carmenrondon benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT michaelrudenko benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT sannatoppilasalmi benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT glenisscadding benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT sophiescheire benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT petervalentintomazic benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT thibautvanzele benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT martinwagemann benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT jobfmvanboven benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper AT philippegevaert benefitsandharmofsystemicsteroidsforshortandlongtermuseinrhinitisandrhinosinusitisaneaacipositionpaper |