A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile
Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Is...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/11/2/339 |
| _version_ | 1797619141507547136 |
|---|---|
| author | Michele M. Moraes Thiago T. Mendes Leandro Borges Alice L. Marques Cristian Núñez-Espinosa Dawit A. P. Gonçalves Carolina B. Simões Tales S. Vieira Roberto V. P. Ladeira Talita G. B. Lourenço Danielle V. Ribeiro Elaine Hatanaka Debora Heller Rosa M. E. Arantes |
| author_facet | Michele M. Moraes Thiago T. Mendes Leandro Borges Alice L. Marques Cristian Núñez-Espinosa Dawit A. P. Gonçalves Carolina B. Simões Tales S. Vieira Roberto V. P. Ladeira Talita G. B. Lourenço Danielle V. Ribeiro Elaine Hatanaka Debora Heller Rosa M. E. Arantes |
| author_sort | Michele M. Moraes |
| collection | DOAJ |
| description | Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Island) and were evaluated at Pre-Camp (i.e., at the beginning of the ship travel), Camp-Initial (i.e., 4th and 5th day in camp), Camp-Middle (i.e., 19th–20th, and 33rd–34th days), Camp-Final (i.e., 45th–46th day), and at the Post-Camp (on the ship). At the Pre-Camp, Camp-Initial, and Camp-Final, we assessed microbiome and inflammatory markers. Catecholamines were accessed Pre- and Post-Camp. Heart rate variability (HRV), leptin, thyroid stimulating hormone (TSH), and thyroxine (T4) were accessed at all time points. Students’ <i>t</i>-tests or repeated-measures analysis of variance (one or two-way ANOVA) followed by Student-Newman-Keuls (<i>post hoc)</i> were used for parametric analysis. Kruskal-Wallis test was applied for non-parametric analysis. Microbiome analysis showed a predominance of <i>Pseudomonadota</i> (34.01%), <i>Bacillota</i> (29.82%), and <i>Bacteroidota</i> (18.54%), followed by <i>Actinomycetota</i> (5.85%), and <i>Fusobacteria</i> (5.74%). Staying in a long-term Antarctic camp resulted in microbiome fluctuations with a reduction in <i>Pseudomonadota</i>—a “microbial signature” of disease. However, the pro-inflammatory marker leptin and IL-8 tended to increase, and the angiogenic factor VEGF was reduced during camp. These results suggest that distinct Antarctic natural environments and behavioral factors modulate oral microbiome and inflammation. |
| first_indexed | 2024-03-11T08:23:53Z |
| format | Article |
| id | doaj.art-29728eb9d7d84d108ce2d2f497637ecc |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-11T08:23:53Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-29728eb9d7d84d108ce2d2f497637ecc2023-11-16T22:14:30ZengMDPI AGMicroorganisms2076-26072023-01-0111233910.3390/microorganisms11020339A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones ProfileMichele M. Moraes0Thiago T. Mendes1Leandro Borges2Alice L. Marques3Cristian Núñez-Espinosa4Dawit A. P. Gonçalves5Carolina B. Simões6Tales S. Vieira7Roberto V. P. Ladeira8Talita G. B. Lourenço9Danielle V. Ribeiro10Elaine Hatanaka11Debora Heller12Rosa M. E. Arantes13Department of Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, BrazilDepartment of Physical Education, Faculty of Education, Universidade Federal da Bahia, Salvador 40170-110, BA, BrazilInterdisciplinary Program in Health Sciences, Universidade Cruzeiro do Sul, São Paulo 01506-000, SP, BrazilPost-Graduation Program in Social Sciences in Development, Culture and Society of the Universidade Federal Rural do Rio de Janeiro, Seropédica 23890-000, RJ, BrazilSchool of Medicine, Universidad de Magallanes, Punta Arenas 6200000, ChileExercise Physiology Laboratory, School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, BrazilExercise Physiology Laboratory, School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, BrazilExercise Physiology Laboratory, School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, BrazilCenter for Newborn Screening and Genetics Diagnosis, Faculty of Medicine, Universidade Federal de Minas Gerais, NUPAD-FM/UFMG, Belo Horizonte 30130-100, MG, BrazilOral Microbiology Laboratory, Institute of Microbiology Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilHospital Israelita Albert Einstein, São Paulo 05652-900, SP, BrazilInterdisciplinary Program in Health Sciences, Universidade Cruzeiro do Sul, São Paulo 01506-000, SP, BrazilHospital Israelita Albert Einstein, São Paulo 05652-900, SP, BrazilDepartment of Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, BrazilAntarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Island) and were evaluated at Pre-Camp (i.e., at the beginning of the ship travel), Camp-Initial (i.e., 4th and 5th day in camp), Camp-Middle (i.e., 19th–20th, and 33rd–34th days), Camp-Final (i.e., 45th–46th day), and at the Post-Camp (on the ship). At the Pre-Camp, Camp-Initial, and Camp-Final, we assessed microbiome and inflammatory markers. Catecholamines were accessed Pre- and Post-Camp. Heart rate variability (HRV), leptin, thyroid stimulating hormone (TSH), and thyroxine (T4) were accessed at all time points. Students’ <i>t</i>-tests or repeated-measures analysis of variance (one or two-way ANOVA) followed by Student-Newman-Keuls (<i>post hoc)</i> were used for parametric analysis. Kruskal-Wallis test was applied for non-parametric analysis. Microbiome analysis showed a predominance of <i>Pseudomonadota</i> (34.01%), <i>Bacillota</i> (29.82%), and <i>Bacteroidota</i> (18.54%), followed by <i>Actinomycetota</i> (5.85%), and <i>Fusobacteria</i> (5.74%). Staying in a long-term Antarctic camp resulted in microbiome fluctuations with a reduction in <i>Pseudomonadota</i>—a “microbial signature” of disease. However, the pro-inflammatory marker leptin and IL-8 tended to increase, and the angiogenic factor VEGF was reduced during camp. These results suggest that distinct Antarctic natural environments and behavioral factors modulate oral microbiome and inflammation.https://www.mdpi.com/2076-2607/11/2/339catecholaminescytokineshuman microbiome phylainflammationmarkersoral microbiome |
| spellingShingle | Michele M. Moraes Thiago T. Mendes Leandro Borges Alice L. Marques Cristian Núñez-Espinosa Dawit A. P. Gonçalves Carolina B. Simões Tales S. Vieira Roberto V. P. Ladeira Talita G. B. Lourenço Danielle V. Ribeiro Elaine Hatanaka Debora Heller Rosa M. E. Arantes A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile Microorganisms catecholamines cytokines human microbiome phyla inflammation markers oral microbiome |
| title | A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
| title_full | A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
| title_fullStr | A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
| title_full_unstemmed | A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
| title_short | A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
| title_sort | 7 week summer camp in antarctica induces fluctuations on human oral microbiome pro inflammatory markers and metabolic hormones profile |
| topic | catecholamines cytokines human microbiome phyla inflammation markers oral microbiome |
| url | https://www.mdpi.com/2076-2607/11/2/339 |
| work_keys_str_mv | AT michelemmoraes a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT thiagotmendes a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT leandroborges a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT alicelmarques a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT cristiannunezespinosa a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT dawitapgoncalves a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT carolinabsimoes a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT talessvieira a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT robertovpladeira a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT talitagblourenco a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT daniellevribeiro a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT elainehatanaka a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT deboraheller a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT rosamearantes a7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT michelemmoraes 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT thiagotmendes 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT leandroborges 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT alicelmarques 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT cristiannunezespinosa 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT dawitapgoncalves 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT carolinabsimoes 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT talessvieira 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT robertovpladeira 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT talitagblourenco 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT daniellevribeiro 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT elainehatanaka 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT deboraheller 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile AT rosamearantes 7weeksummercampinantarcticainducesfluctuationsonhumanoralmicrobiomeproinflammatorymarkersandmetabolichormonesprofile |