Perinatal Lead Exposure Promotes Sex-Specific Epigenetic Programming of Disease-Relevant Pathways in Mouse Heart

Perinatal Lead Exposure Promotes Sex-Specific Epigenetic Programming of Disease-Relevant Pathways in Mouse Heart

Environmental contaminants such as the metal lead (Pb) are associated with cardiovascular disease, but the underlying molecular mechanisms are poorly understood. In particular, little is known about how exposure to Pb during early development impacts the cardiac epigenome at any point across the lif...

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Bibliographic Details
Main Authors:	Laurie K. Svoboda, Kai Wang, Jaclyn M. Goodrich, Tamara R. Jones, Justin A. Colacino, Karen E. Peterson, Martha M. Tellez-Rojo, Maureen A. Sartor, Dana C. Dolinoy
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	Toxics
Subjects:	heart cardiovascular disease DNA methylation epigenetic Developmental Origins of Health and Disease (DOHaD) toxicoepigenetics
Online Access:	https://www.mdpi.com/2305-6304/11/1/85

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