Bioactivity of Spongian Diterpenoid Scaffolds from the Antarctic Sponge <i>Dendrilla antarctica</i>

Bioactivity of Spongian Diterpenoid Scaffolds from the Antarctic Sponge <i>Dendrilla antarctica</i>

The Antarctic sponge <i>Dendrilla antarctica</i> is rich in defensive terpenoids with promising antimicrobial potential. Investigation of this demosponge has resulted in the generation of a small chemical library containing diterpenoid secondary metabolites with bioactivity in an infecti...

Full description

Bibliographic Details
Main Authors:	Alexandre Bory, Andrew J. Shilling, Jessie Allen, Ala Azhari, Alison Roth, Lindsey N. Shaw, Dennis E. Kyle, John H. Adams, Charles D. Amsler, James B. McClintock, Bill J. Baker
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Marine Drugs
Subjects:	diterpenoids dendrillins malaria leishmaniasis MRSA biofilm
Online Access:	https://www.mdpi.com/1660-3397/18/6/327

Similar Items

Chemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge <i>Dendrilla antarctica</i>
by: Andrea Prófumo, et al.
Published: (2024-12-01)

A Chemo-Ecological Investigation of <i>Dendrilla antarctica</i> Topsent, 1905: Identification of Deceptionin and the Effects of Heat Stress and Predation Pressure on Its Terpene Profiles
by: Paula De Castro-Fernández, et al.
Published: (2023-09-01)

From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica
by: Alessio Ottaviani, et al.
Published: (2022-12-01)

Two New Seco-Labdane Diterpenoids from the Leaves of <i>Callicarpa nudiflora</i>
by: Xia Guo, et al.
Published: (2022-06-01)

Phytochemistry and Pharmacological Activities of the Diterpenoids from the Genus <i>Daphne</i>
by: Yi-Wen Nie, et al.
Published: (2021-10-01)

Nitrogen-Containing Diterpenoids, Sesquiterpenoids, and Nor-Diterpenoids from Cespitularia taeniata
by: Shih-Sheng Wang, et al.
Published: (2015-09-01)

Structure, Absolute Configuration, Antiproliferative and Phytotoxic Activities of Icetexane and Abietane Diterpenoids from <i>Salvia carranzae</i> and Chemotaxonomic Implications
by: Celia Bustos-Brito, et al.
Published: (2024-03-01)

Diterpenoids from <i>Blumea balsamifera</i> and Their Anti-Inflammatory Activities
by: Xiao-Ling Huang, et al.
Published: (2022-04-01)

Novel Diterpenoids from the Twigs of Podocarpus nagi
by: Yuan-Dong Zheng, et al.
Published: (2016-09-01)

Enhancing Crop Resilience: Insights from Labdane-Related Diterpenoid Phytoalexin Research in Rice (<i>Oryza sativa</i> L.)
by: Shiquan Bian, et al.
Published: (2024-09-01)

Bioactive Diterpenoids from Clerodendrum kiangsiense
by: Mingfeng Xu, et al.
Published: (2016-01-01)

Metabolism of Diterpenoids Derived from the Bark of <i>Cinnamomum cassia</i> in Human Liver Microsomes
by: Su Min Choi, et al.
Published: (2021-08-01)

The Anti-Arthritic Potential of the Ethanolic Extract of <i>Salvia Lachnostachys</i> Benth. Leaves and Icetexane Dinor-Diterpenoid Fruticuline B
by: Natália de M. Balsalobre, et al.
Published: (2024-09-01)

<i>Ent</i>-Abietane Diterpenoids from <i>Euphorbia fischeriana</i> and Their Cytotoxic Activities
by: Qin-Feng Zhu, et al.
Published: (2022-10-01)

Clerodane Diterpenoids from <i>Callicarpa hypoleucophylla</i> and Their Anti-Inflammatory Activity
by: Yu-Chi Lin, et al.
Published: (2020-05-01)

Abietane-Type Diterpenoids from the Arils of <i>Torreya grandis</i>
by: Yuqi Gao, et al.
Published: (2024-04-01)

Recent Advances in the Application of Diterpenoids in the Preservation of Meat Products
by: YAN Jinxi, ZANG Mingwu, LIU He, XU Chenchen, SHI Yuxuan, BAI Jing, ZHAO Yan, HAO Jingyi, ZHANG Yaru
Published: (2024-07-01)

New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
by: Shang-Kwei Wang, et al.
Published: (2013-10-01)

Diterpenoids from the Aerial Parts of <i>Isodon serra</i> with Selective Cytotoxic Activity
by: Siqin Li, et al.
Published: (2024-06-01)

Diterpenoid Alkaloids Isolated from <i>Delphinium brunonianum</i> and Their Inhibitory Effects on Hepatocytes Lipid Accumulation
by: Huanhuan Ma, et al.
Published: (2022-03-01)

Anti-Inflammatory Cembrane-Type Diterpenoids and Prostaglandins from Soft Coral <i>Lobophytum sarcophytoides</i>
by: Hongjie Shen, et al.
Published: (2019-08-01)

Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology
by: Angel de Jesús Dzul-Beh, et al.
Published: (2020-09-01)

The chemical structures and biological activities of indole diterpenoids
by: Jingwen Niu, et al.
Published: (2023-01-01)

Discovery of Novel Diterpenoids from Sinularia arborea
by: Kuan-Hua Chen, et al.
Published: (2014-01-01)

HỢP CHẤT DITERPENOID VÀ FLAVONOID TỪ LÁ BÌNH BÁT NƯỚC ANNONA GLABRA L. (ANONACEAE)
by: Phạm Thị Nhật Trinh, et al.
Published: (2014-10-01)

Antimycobacterial, Cytotoxic, and Antioxidant Activities of Abietane Diterpenoids Isolated from <i>Plectranthus madagascariensis</i>
by: Kadidiatou O. Ndjoubi, et al.
Published: (2021-01-01)

A new labdane-type diterpenoid from leaves of Vitex rotundifolia
by: Yusuke Hanaki, et al.
Published: (2024-01-01)

Hidden Diversity in an Antarctic Algal Forest: Metabolomic Profiling Linked to Patterns of Genetic Diversification in the Antarctic Red Alga <i>Plocamium</i> sp.
by: Andrew J. Shilling, et al.
Published: (2021-10-01)

Geliboluols A–D: Kaurane-Type Diterpenoids from the Marine-Derived Rare Actinomycete <i>Actinomadura geliboluensis</i>
by: Chang-Su Heo, et al.
Published: (2025-02-01)

Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
by: Shi-Fei Li, et al.
Published: (2016-04-01)

An Anti-Inflammatory 2,4-Cyclized-3,4-Secospongian Diterpenoid and Furanoterpene-Related Metabolites of a Marine Sponge <i>Spongia</i> sp. from the Red Sea
by: Chi-Jen Tai, et al.
Published: (2021-01-01)

A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados
by: Yun-Sheng Lin, et al.
Published: (2013-01-01)

Flexibilins A–C, New Cembrane-Type Diterpenoids from the Formosan Soft Coral, Sinularia flexibilis
by: Ping-Jyun Sung, et al.
Published: (2013-06-01)

Cespitulones A and B, Cytotoxic Diterpenoids of a New Structure Class from the Soft Coral Cespitularia taeniata
by: Yu-Chi Lin, et al.
Published: (2014-06-01)

Identification of Gene Candidates in Diterpenoid Biosynthesis of Curcuma longa: An mRNA Sequencing Approach
by: Hafizh Fadhullah, et al.
Published: (2024-09-01)

New Antibacterial Diterpenoids from the South China Sea Soft Coral <i>Klyxum molle</i>
by: Jia-Dong Yu, et al.
Published: (2023-06-01)

Ximaoornatins A–C, Polyoxygenated Diterpenoids from the Hainan Soft Coral <i>Sinularia ornata</i>
by: Li-Li Sun, et al.
Published: (2022-03-01)

<i>Rugulopteryx</i>-Derived Spatane, Secospatane, Prenylcubebane and Prenylkelsoane Diterpenoids as Inhibitors of Nitric Oxide Production
by: Belén Cuevas, et al.
Published: (2023-04-01)

New Sesterterpenes from the Antarctic Sponge <i>Suberites</i> sp.
by: Stine S. H. Olsen, et al.
Published: (2024-12-01)

Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
by: Katsuhiro Ueda, et al.
Published: (2012-11-01)