Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria
Macrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing. Here, we review recent discoveries and emerging concepts on bacterial molecular strategies to subvert macrophage immune responses. We foc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-09-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fcimb.2020.577559/full |
| _version_ | 1818112525838843904 |
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| author | Clarisse Leseigneur Clarisse Leseigneur Pierre Lê-Bury Pierre Lê-Bury Javier Pizarro-Cerdá Javier Pizarro-Cerdá Javier Pizarro-Cerdá Olivier Dussurget Olivier Dussurget |
| author_facet | Clarisse Leseigneur Clarisse Leseigneur Pierre Lê-Bury Pierre Lê-Bury Javier Pizarro-Cerdá Javier Pizarro-Cerdá Javier Pizarro-Cerdá Olivier Dussurget Olivier Dussurget |
| author_sort | Clarisse Leseigneur |
| collection | DOAJ |
| description | Macrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing. Here, we review recent discoveries and emerging concepts on bacterial molecular strategies to subvert macrophage immune responses. We focus on the expanding number of fascinating subversive tools developed by Listeria monocytogenes, Staphylococcus aureus, and pathogenic Yersinia spp., illustrating diversity and commonality in mechanisms used by microorganisms with different pathogenic lifestyles. |
| first_indexed | 2024-12-11T03:20:20Z |
| format | Article |
| id | doaj.art-29760559c4094955a55a9ab1822fc98b |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-11T03:20:20Z |
| publishDate | 2020-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-29760559c4094955a55a9ab1822fc98b2022-12-22T01:22:38ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882020-09-011010.3389/fcimb.2020.577559577559Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic BacteriaClarisse Leseigneur0Clarisse Leseigneur1Pierre Lê-Bury2Pierre Lê-Bury3Javier Pizarro-Cerdá4Javier Pizarro-Cerdá5Javier Pizarro-Cerdá6Olivier Dussurget7Olivier Dussurget8Unité de Recherche Yersinia, Institut Pasteur, Paris, FranceUniversité de Paris, Sorbonne Paris Cité, Paris, FranceUnité de Recherche Yersinia, Institut Pasteur, Paris, FranceUniversité de Paris, Sorbonne Paris Cité, Paris, FranceUnité de Recherche Yersinia, Institut Pasteur, Paris, FranceNational Reference Laboratory Plague & Other Yersiniosis, Institut Pasteur, Paris, FranceWHO Collaborative Research & Reference Centre for Yersinia, Institut Pasteur, Paris, FranceUnité de Recherche Yersinia, Institut Pasteur, Paris, FranceUniversité de Paris, Sorbonne Paris Cité, Paris, FranceMacrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing. Here, we review recent discoveries and emerging concepts on bacterial molecular strategies to subvert macrophage immune responses. We focus on the expanding number of fascinating subversive tools developed by Listeria monocytogenes, Staphylococcus aureus, and pathogenic Yersinia spp., illustrating diversity and commonality in mechanisms used by microorganisms with different pathogenic lifestyles.https://www.frontiersin.org/article/10.3389/fcimb.2020.577559/fullphagocyteimmune escapevirulencelisteriosisstaphylococcal infectionplague |
| spellingShingle | Clarisse Leseigneur Clarisse Leseigneur Pierre Lê-Bury Pierre Lê-Bury Javier Pizarro-Cerdá Javier Pizarro-Cerdá Javier Pizarro-Cerdá Olivier Dussurget Olivier Dussurget Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria Frontiers in Cellular and Infection Microbiology phagocyte immune escape virulence listeriosis staphylococcal infection plague |
| title | Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria |
| title_full | Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria |
| title_fullStr | Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria |
| title_full_unstemmed | Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria |
| title_short | Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria |
| title_sort | emerging evasion mechanisms of macrophage defenses by pathogenic bacteria |
| topic | phagocyte immune escape virulence listeriosis staphylococcal infection plague |
| url | https://www.frontiersin.org/article/10.3389/fcimb.2020.577559/full |
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