Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice

Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice

Lipid overload contributes to cardiac complications of diabetes and obesity. However, the underlying mechanisms remain obscure. This study investigates the role of gamma-aminobutyrate transaminase (ABAT), the key enzyme involved in the catabolism of γ-aminobutyric acid (GABA), in lipid overload-indu...

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Bibliographic Details
Main Authors:	Mengxiao Zhang, Huiting Zhong, Ting Cao, Yifan Huang, Xiaoyun Ji, Guo-Chang Fan, Tianqing Peng
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	lipid overload ABAT mitochondrial dysfunction heart dysfunction apoptosis cardiomyocytes
Online Access:	https://www.mdpi.com/1422-0067/23/4/2182

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