Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients
BackgroundDiabetes mellitus is a major independent risk factor for cardiovascular disease (CVD), but high cardiovascular risk in diabetes mellitus patients is not completely explained by clustering traditional risk factors. Recently, associations between diabetic polyneuropathy (DPN) and macrovascul...
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| Format: | Article |
| Language: | English |
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Korean Diabetes Association
2011-08-01
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| Series: | Diabetes & Metabolism Journal |
| Subjects: | |
| Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-390.pdf |
| _version_ | 1819021608287731712 |
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| author | Jin Ook Chung Dong Hyeok Cho Dong Jin Chung Min Young Chung |
| author_facet | Jin Ook Chung Dong Hyeok Cho Dong Jin Chung Min Young Chung |
| author_sort | Jin Ook Chung |
| collection | DOAJ |
| description | BackgroundDiabetes mellitus is a major independent risk factor for cardiovascular disease (CVD), but high cardiovascular risk in diabetes mellitus patients is not completely explained by clustering traditional risk factors. Recently, associations between diabetic polyneuropathy (DPN) and macrovasculopathy have been suggested. We aimed to assess associations between DPN and cardiovascular complications in type 2 diabetic patients.MethodsMicrovascular and cardiovascular complications were evaluated in 1,041 type 2 diabetic patients.ResultsIn patients with DPN, the age, prevalence of hypertension, diabetes duration, systolic blood pressure, pulse pressure, and hemoglobin glycation (HbA1c) levels were significantly higher, while the high density lipoprotein cholesterol (HDL-C) levels were lower than in those without DPN. The prevalence of CVD was higher in patients with DPN. In multivariate analysis, DPN was independently associated with CVD (odds ratio, 1.801; 95% confidence interval, 1.009 to 3.214).ConclusionOur results showed that DPN was associated with a high prevalence of cardiovascular disease in type 2 diabetic patients, but further studies are needed to investigate the causative nature of associations between DPN and CVD. |
| first_indexed | 2024-12-21T04:09:48Z |
| format | Article |
| id | doaj.art-297a18bb03e4426e93ccfcea498d39e7 |
| institution | Directory Open Access Journal |
| issn | 2233-6079 2233-6087 |
| language | English |
| last_indexed | 2024-12-21T04:09:48Z |
| publishDate | 2011-08-01 |
| publisher | Korean Diabetes Association |
| record_format | Article |
| series | Diabetes & Metabolism Journal |
| spelling | doaj.art-297a18bb03e4426e93ccfcea498d39e72022-12-21T19:16:29ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872011-08-0135439039610.4093/dmj.2011.35.4.3902669Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic PatientsJin Ook ChungDong Hyeok ChoDong Jin ChungMin Young ChungBackgroundDiabetes mellitus is a major independent risk factor for cardiovascular disease (CVD), but high cardiovascular risk in diabetes mellitus patients is not completely explained by clustering traditional risk factors. Recently, associations between diabetic polyneuropathy (DPN) and macrovasculopathy have been suggested. We aimed to assess associations between DPN and cardiovascular complications in type 2 diabetic patients.MethodsMicrovascular and cardiovascular complications were evaluated in 1,041 type 2 diabetic patients.ResultsIn patients with DPN, the age, prevalence of hypertension, diabetes duration, systolic blood pressure, pulse pressure, and hemoglobin glycation (HbA1c) levels were significantly higher, while the high density lipoprotein cholesterol (HDL-C) levels were lower than in those without DPN. The prevalence of CVD was higher in patients with DPN. In multivariate analysis, DPN was independently associated with CVD (odds ratio, 1.801; 95% confidence interval, 1.009 to 3.214).ConclusionOur results showed that DPN was associated with a high prevalence of cardiovascular disease in type 2 diabetic patients, but further studies are needed to investigate the causative nature of associations between DPN and CVD.http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-390.pdfCardiovascular diseasesDiabetes mellitus, type 2Diabetic neuropathies |
| spellingShingle | Jin Ook Chung Dong Hyeok Cho Dong Jin Chung Min Young Chung Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients Diabetes & Metabolism Journal Cardiovascular diseases Diabetes mellitus, type 2 Diabetic neuropathies |
| title | Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients |
| title_full | Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients |
| title_fullStr | Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients |
| title_full_unstemmed | Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients |
| title_short | Association between Diabetic Polyneuropathy and Cardiovascular Complications in Type 2 Diabetic Patients |
| title_sort | association between diabetic polyneuropathy and cardiovascular complications in type 2 diabetic patients |
| topic | Cardiovascular diseases Diabetes mellitus, type 2 Diabetic neuropathies |
| url | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-390.pdf |
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