A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma
Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramed...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-04-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096241242237 |
| _version_ | 1797221332544389120 |
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| author | Lefika Bathobakae MD, MPH Shayee Hasan MD Aneeqa Shahid MD Tyler Wilkinson MSc Shajla Ajas MD Mehandar Kumar MD Sohail Qayyum MD Amer Akmal MD |
| author_facet | Lefika Bathobakae MD, MPH Shayee Hasan MD Aneeqa Shahid MD Tyler Wilkinson MSc Shajla Ajas MD Mehandar Kumar MD Sohail Qayyum MD Amer Akmal MD |
| author_sort | Lefika Bathobakae MD, MPH |
| collection | DOAJ |
| description | Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient’s age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors. |
| first_indexed | 2024-04-24T13:03:45Z |
| format | Article |
| id | doaj.art-297c45868dfd4b2ba692cd6feeb6f132 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-04-24T13:03:45Z |
| publishDate | 2024-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-297c45868dfd4b2ba692cd6feeb6f1322024-04-05T09:03:40ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962024-04-011210.1177/23247096241242237A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic EnigmaLefika Bathobakae MD, MPH0Shayee Hasan MD1Aneeqa Shahid MD2Tyler Wilkinson MSc3Shajla Ajas MD4Mehandar Kumar MD5Sohail Qayyum MD6Amer Akmal MD7St. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. George’s University School of Medicine, Grenada, West IndiesSt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USAPlasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient’s age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors.https://doi.org/10.1177/23247096241242237 |
| spellingShingle | Lefika Bathobakae MD, MPH Shayee Hasan MD Aneeqa Shahid MD Tyler Wilkinson MSc Shajla Ajas MD Mehandar Kumar MD Sohail Qayyum MD Amer Akmal MD A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma Journal of Investigative Medicine High Impact Case Reports |
| title | A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma |
| title_full | A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma |
| title_fullStr | A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma |
| title_full_unstemmed | A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma |
| title_short | A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma |
| title_sort | plasmacytoma of the lateral pharyngeal wall a diagnostic enigma |
| url | https://doi.org/10.1177/23247096241242237 |
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