Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone
Polycaprolactone (PCL) is a resorbable semicrystalline polymer that degrades slowly via hydrolysis and has applications in medical implants and drug delivery. As a result of its low melting point, PCL can be processed easily by conventional polymer processing techniques. However, the additive manufa...
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| Format: | Article |
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MDPI AG
2020-05-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/9/3189 |
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| author | Jian-Ming Chen Demei Lee Jheng-Wei Yang Sheng-Han Lin Yu-Ting Lin Shih-Jung Liu |
| author_facet | Jian-Ming Chen Demei Lee Jheng-Wei Yang Sheng-Han Lin Yu-Ting Lin Shih-Jung Liu |
| author_sort | Jian-Ming Chen |
| collection | DOAJ |
| description | Polycaprolactone (PCL) is a resorbable semicrystalline polymer that degrades slowly via hydrolysis and has applications in medical implants and drug delivery. As a result of its low melting point, PCL can be processed easily by conventional polymer processing techniques. However, the additive manufacturing of PCL remains a challenge, mainly due to the fact that there are no commercially available filaments for traditional fused deposition modeling (FDM). Furthermore, when the materials are fabricated via FDM for drug delivery applications, the high temperature may deactivate the incorporated drugs/biomolecules. This study investigates the solution extrusion additive manufacturing of PCL using a lab-developed solution-type device. The device comprises a solution extrusion feeder, driving stepper motors, a power source, a syringe equipped with a dispensing tip, an accumulation platform, and a control interface. The influences of different manufacturing parameters on part quality were evaluated. The experimental results suggest that the tensile strength of the additively manufactured parts increases with fill density but decreases with the ratio of PCL to dichloromethane (DCM) and moving speed of the dispensing tip. Parts fabricated by 90° print orientation of infill exhibited the greatest mechanical strength. The fabricated parts tend to heal the gaps among strips after additive manufacturing, but tiny pores can still be seen on the surfaces. |
| first_indexed | 2024-03-10T20:03:11Z |
| format | Article |
| id | doaj.art-29837346178a4d8aa61007e8c1c4b079 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T20:03:11Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-29837346178a4d8aa61007e8c1c4b0792023-11-19T23:24:16ZengMDPI AGApplied Sciences2076-34172020-05-01109318910.3390/app10093189Solution Extrusion Additive Manufacturing of Biodegradable PolycaprolactoneJian-Ming Chen0Demei Lee1Jheng-Wei Yang2Sheng-Han Lin3Yu-Ting Lin4Shih-Jung Liu5Department of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, TaiwanPolycaprolactone (PCL) is a resorbable semicrystalline polymer that degrades slowly via hydrolysis and has applications in medical implants and drug delivery. As a result of its low melting point, PCL can be processed easily by conventional polymer processing techniques. However, the additive manufacturing of PCL remains a challenge, mainly due to the fact that there are no commercially available filaments for traditional fused deposition modeling (FDM). Furthermore, when the materials are fabricated via FDM for drug delivery applications, the high temperature may deactivate the incorporated drugs/biomolecules. This study investigates the solution extrusion additive manufacturing of PCL using a lab-developed solution-type device. The device comprises a solution extrusion feeder, driving stepper motors, a power source, a syringe equipped with a dispensing tip, an accumulation platform, and a control interface. The influences of different manufacturing parameters on part quality were evaluated. The experimental results suggest that the tensile strength of the additively manufactured parts increases with fill density but decreases with the ratio of PCL to dichloromethane (DCM) and moving speed of the dispensing tip. Parts fabricated by 90° print orientation of infill exhibited the greatest mechanical strength. The fabricated parts tend to heal the gaps among strips after additive manufacturing, but tiny pores can still be seen on the surfaces.https://www.mdpi.com/2076-3417/10/9/3189polycaprolactoneadditive manufacturingsolution extrusionmanufacturing parameter |
| spellingShingle | Jian-Ming Chen Demei Lee Jheng-Wei Yang Sheng-Han Lin Yu-Ting Lin Shih-Jung Liu Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone Applied Sciences polycaprolactone additive manufacturing solution extrusion manufacturing parameter |
| title | Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone |
| title_full | Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone |
| title_fullStr | Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone |
| title_full_unstemmed | Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone |
| title_short | Solution Extrusion Additive Manufacturing of Biodegradable Polycaprolactone |
| title_sort | solution extrusion additive manufacturing of biodegradable polycaprolactone |
| topic | polycaprolactone additive manufacturing solution extrusion manufacturing parameter |
| url | https://www.mdpi.com/2076-3417/10/9/3189 |
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