A novel approach for the purification of aggregation prone proteins.
The protein aggregation is one of the major challenges of the biotechnological industry, especially in the areas of development and commercialization of successful protein-based drug products. The inherent high aggregation tendency of proteins during various manufacturing processes, storage, and adm...
Main Authors: | Austin Royster, Sheema Mir, Mohammad Ayoub Mir |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0260143 |
Similar Items
-
Modulations in the host cell proteome by the hantavirus nucleocapsid protein.
by: Austin Royster, et al.
Published: (2024-01-01) -
SARS-CoV-2 Nucleocapsid Protein Is a Potential Therapeutic Target for Anticoronavirus Drug Discovery
by: Austin Royster, et al.
Published: (2023-06-01) -
Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases
by: Gareth S.A. Wright, et al.
Published: (2020-06-01) -
The mRNA vaccine, a swift warhead against a moving infectious disease target
by: Sheema Mir, et al.
Published: (2024-12-01) -
One-step affinity purification of fusion proteins with optimal monodispersity and biological activity: application to aggregation-prone HPV E6 proteins
by: Anna Bonhoure, et al.
Published: (2018-12-01)