Utility of constraints reflecting system stability on analyses for biological models.

Simulating complex biological models consisting of multiple ordinary differential equations can aid in the prediction of the pharmacological/biological responses; however, they are often hampered by the availability of reliable kinetic parameters. In the present study, we aimed to discover the prope...

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Bibliographic Details
Main Authors: Yoshiaki Kariya, Masashi Honma, Keita Tokuda, Akihiko Konagaya, Hiroshi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010441

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