A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention

Background Substance use disorders negatively affect global disease burden. Effective preventive interventions are available, but whether they provide value for money is unclear. Aims This review looks at the cost-effectiveness evidence of preventive interventions for cannabis use, opioid misuse an...

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Main Authors: Jan Faller, Long Khanh-Dao Le, Mary Lou Chatterton, Joahna Kevin Perez, Oxana Chiotelis, Huong Ngoc Quynh Tran, Marufa Sultana, Natasha Hall, Yong Yi Lee, Cath Chapman, Nicola Newton, Tim Slade, Matt Sunderland, Maree Teesson, Cathrine Mihalopoulos
Format: Article
Language:English
Published: Cambridge University Press 2023-09-01
Series:BJPsych Open
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S205647242300515X/type/journal_article
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author Jan Faller
Long Khanh-Dao Le
Mary Lou Chatterton
Joahna Kevin Perez
Oxana Chiotelis
Huong Ngoc Quynh Tran
Marufa Sultana
Natasha Hall
Yong Yi Lee
Cath Chapman
Nicola Newton
Tim Slade
Matt Sunderland
Maree Teesson
Cathrine Mihalopoulos
author_facet Jan Faller
Long Khanh-Dao Le
Mary Lou Chatterton
Joahna Kevin Perez
Oxana Chiotelis
Huong Ngoc Quynh Tran
Marufa Sultana
Natasha Hall
Yong Yi Lee
Cath Chapman
Nicola Newton
Tim Slade
Matt Sunderland
Maree Teesson
Cathrine Mihalopoulos
author_sort Jan Faller
collection DOAJ
description Background Substance use disorders negatively affect global disease burden. Effective preventive interventions are available, but whether they provide value for money is unclear. Aims This review looks at the cost-effectiveness evidence of preventive interventions for cannabis use, opioid misuse and illicit drug use. Method Literature search was undertaken in Medline, CINAHL, PsycINFO, EconLit through EBSCOhost and EMBASE, up to May 2021. Grey literature search was conducted as supplement. Studies included were full economic evaluations or return-on-investment (ROI) analyses for preventing opioid misuse, cannabis and illicit drug use. English-language restriction was used. Outcomes extracted were incremental cost-effectiveness ratios (ICER) or ROI ratios, with costs presented in 2019 United States dollars. Quality was assessed with the Drummond checklist. Results Eleven full economic evaluation studies were identified from 5674 citations, with all studies conducted in high-income countries. Most aimed to prevent opioid misuse (n = 4), cannabis (n = 3) or illicit drug use (n = 5). Modelling was the predominant methodology (n = 7). Five evaluated school-based universal interventions targeting children and adolescents (aged <18 years). Five cost–benefit studies reported cost-savings. One cost-effectiveness and two cost–utility analysis studies supported the cost-effectiveness of interventions, as ICERs fell under prespecified value-for-money thresholds. Conclusions There are limited economic evaluations of preventive interventions for opioid misuse, cannabis and illicit drug use. Family-based intervention (ParentCorps), school-based interventions (Social and Emotional Training and Project ALERT) and a doctor's programme to assess patient risk of misusing narcotics (‘the Network System to Prevent Doctor-Shopping for Narcotics’) show promising cost-effectiveness and warrant consideration.
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spelling doaj.art-2998100f81f4482f8d0537bd5275c1062023-08-08T06:46:44ZengCambridge University PressBJPsych Open2056-47242023-09-01910.1192/bjo.2023.515A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use preventionJan Faller0https://orcid.org/0000-0001-7645-2079Long Khanh-Dao Le1https://orcid.org/0000-0002-9442-6824Mary Lou Chatterton2Joahna Kevin Perez3Oxana Chiotelis4Huong Ngoc Quynh Tran5Marufa Sultana6Natasha Hall7Yong Yi Lee8Cath Chapman9Nicola Newton10Tim Slade11Matt Sunderland12Maree Teesson13Cathrine Mihalopoulos14Monash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, AustraliaMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, AustraliaMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, AustraliaMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, AustraliaDeakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, AustraliaDeakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, AustraliaDeakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, AustraliaDeakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, AustraliaMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Australia; School of Public Health, The University of Queensland, Australia; and Policy and Epidemiology Group, Queensland Centre for Mental Health Research, Wacol, Queensland, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, AustraliaMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Australia; and Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, AustraliaBackground Substance use disorders negatively affect global disease burden. Effective preventive interventions are available, but whether they provide value for money is unclear. Aims This review looks at the cost-effectiveness evidence of preventive interventions for cannabis use, opioid misuse and illicit drug use. Method Literature search was undertaken in Medline, CINAHL, PsycINFO, EconLit through EBSCOhost and EMBASE, up to May 2021. Grey literature search was conducted as supplement. Studies included were full economic evaluations or return-on-investment (ROI) analyses for preventing opioid misuse, cannabis and illicit drug use. English-language restriction was used. Outcomes extracted were incremental cost-effectiveness ratios (ICER) or ROI ratios, with costs presented in 2019 United States dollars. Quality was assessed with the Drummond checklist. Results Eleven full economic evaluation studies were identified from 5674 citations, with all studies conducted in high-income countries. Most aimed to prevent opioid misuse (n = 4), cannabis (n = 3) or illicit drug use (n = 5). Modelling was the predominant methodology (n = 7). Five evaluated school-based universal interventions targeting children and adolescents (aged <18 years). Five cost–benefit studies reported cost-savings. One cost-effectiveness and two cost–utility analysis studies supported the cost-effectiveness of interventions, as ICERs fell under prespecified value-for-money thresholds. Conclusions There are limited economic evaluations of preventive interventions for opioid misuse, cannabis and illicit drug use. Family-based intervention (ParentCorps), school-based interventions (Social and Emotional Training and Project ALERT) and a doctor's programme to assess patient risk of misusing narcotics (‘the Network System to Prevent Doctor-Shopping for Narcotics’) show promising cost-effectiveness and warrant consideration. https://www.cambridge.org/core/product/identifier/S205647242300515X/type/journal_articleIllicit drug useopioidcannabiseconomic evaluationprevention
spellingShingle Jan Faller
Long Khanh-Dao Le
Mary Lou Chatterton
Joahna Kevin Perez
Oxana Chiotelis
Huong Ngoc Quynh Tran
Marufa Sultana
Natasha Hall
Yong Yi Lee
Cath Chapman
Nicola Newton
Tim Slade
Matt Sunderland
Maree Teesson
Cathrine Mihalopoulos
A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
BJPsych Open
Illicit drug use
opioid
cannabis
economic evaluation
prevention
title A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
title_full A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
title_fullStr A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
title_full_unstemmed A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
title_short A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
title_sort systematic review of economic evaluations for opioid misuse cannabis and illicit drug use prevention
topic Illicit drug use
opioid
cannabis
economic evaluation
prevention
url https://www.cambridge.org/core/product/identifier/S205647242300515X/type/journal_article
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