An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2
Abstract Granulomas often form around pathogens that cause chronic infections. Here, we discover an innate granuloma model in mice with an environmental bacterium called Chromobacterium violaceum. Granuloma formation not only successfully walls off, but also clears, the infection. The infected lesio...
Main Authors: | Carissa K. Harvest, Taylor J. Abele, Chen Yu, Cole J. Beatty, Megan E. Amason, Zachary P. Billman, Morgan A. DePrizio, Fernando W. Souza, Carolyn A. Lacey, Vivien I. Maltez, Heather N. Larson, Benjamin D. McGlaughon, Daniel R. Saban, Stephanie A. Montgomery, Edward A. Miao |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-42218-1 |
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