Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis

A 28-year-old male patient who was a nonsmoker presented with bilateral symmetrical polyarthritis and polyarthralgia, suggestive of rheumatoid arthritis (RA), along with shortness of breath, fever and cough, suggestive of chronic renal failure and nephrotic range proteinuria. The chest radiograph wa...

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Main Authors: Arunabha D Chaudhuri, Sumit R Tapadar, Saurav Kar, Sayantan Saha
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Saudi Journal of Medicine and Medical Sciences
Subjects:
Online Access:http://www.sjmms.net/article.asp?issn=1658-631X;year=2017;volume=5;issue=3;spage=271;epage=274;aulast=Chaudhuri
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author Arunabha D Chaudhuri
Sumit R Tapadar
Saurav Kar
Sayantan Saha
author_facet Arunabha D Chaudhuri
Sumit R Tapadar
Saurav Kar
Sayantan Saha
author_sort Arunabha D Chaudhuri
collection DOAJ
description A 28-year-old male patient who was a nonsmoker presented with bilateral symmetrical polyarthritis and polyarthralgia, suggestive of rheumatoid arthritis (RA), along with shortness of breath, fever and cough, suggestive of chronic renal failure and nephrotic range proteinuria. The chest radiograph was suggestive of panacinar emphysematous changes with bilateral central bronchiectasis. The patient reported that two of his brothers had died in their third decade because of renal failure. Renal biopsy showed focal and segmental glomerulosclerosis (FSGS). FSGS with panacinar emphysema and bronchiectasis is a rare entity in RA patients, and considering the possibilities of a familial pattern of FSGS, transient receptor potential cation channel 6 channelopathy was the most valid diagnosis.
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spelling doaj.art-299c844d95a04fe6a3ea219b3a17f51c2022-12-22T01:32:08ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2017-01-015327127410.4103/1658-631X.213303Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritisArunabha D ChaudhuriSumit R TapadarSaurav KarSayantan SahaA 28-year-old male patient who was a nonsmoker presented with bilateral symmetrical polyarthritis and polyarthralgia, suggestive of rheumatoid arthritis (RA), along with shortness of breath, fever and cough, suggestive of chronic renal failure and nephrotic range proteinuria. The chest radiograph was suggestive of panacinar emphysematous changes with bilateral central bronchiectasis. The patient reported that two of his brothers had died in their third decade because of renal failure. Renal biopsy showed focal and segmental glomerulosclerosis (FSGS). FSGS with panacinar emphysema and bronchiectasis is a rare entity in RA patients, and considering the possibilities of a familial pattern of FSGS, transient receptor potential cation channel 6 channelopathy was the most valid diagnosis.http://www.sjmms.net/article.asp?issn=1658-631X;year=2017;volume=5;issue=3;spage=271;epage=274;aulast=ChaudhuriBronchiectasisfocal and segmental glomerulosclerosisrheumatoid arthritistransient receptor potential cation channel 6 channelopathy
spellingShingle Arunabha D Chaudhuri
Sumit R Tapadar
Saurav Kar
Sayantan Saha
Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
Saudi Journal of Medicine and Medical Sciences
Bronchiectasis
focal and segmental glomerulosclerosis
rheumatoid arthritis
transient receptor potential cation channel 6 channelopathy
title Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
title_full Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
title_fullStr Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
title_full_unstemmed Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
title_short Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
title_sort bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis
topic Bronchiectasis
focal and segmental glomerulosclerosis
rheumatoid arthritis
transient receptor potential cation channel 6 channelopathy
url http://www.sjmms.net/article.asp?issn=1658-631X;year=2017;volume=5;issue=3;spage=271;epage=274;aulast=Chaudhuri
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AT sumitrtapadar bronchiectasisandfocalsegmentalglomerulosclerosisinrheumatoidarthritis
AT sauravkar bronchiectasisandfocalsegmentalglomerulosclerosisinrheumatoidarthritis
AT sayantansaha bronchiectasisandfocalsegmentalglomerulosclerosisinrheumatoidarthritis