Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton

Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton

Herpes simplex virus type 1 (HSV-1) is a neuroinvasive human pathogen that has the ability to infect and replicate within epithelial cells and neurons and establish a life-long latent infection in sensory neurons. HSV-1 depends on the host cellular cytoskeleton for entry, replication, and exit. Ther...

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Bibliographic Details
Main Authors: Monica Miranda-Saksena, Christopher E. Denes, Russell J. Diefenbach, Anthony L. Cunningham
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Viruses
Subjects:
herpes simplex virus
neurons
axonal transport
cytoskeleton
microtubules
actin
Online Access:http://www.mdpi.com/1999-4915/10/2/92

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