Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson's disease model
Understanding the mechanism(s) by which dopaminergic (DAergic) neurons are eroded in Parkinson's disease (PD) is critical for effective therapeutic strategies. By using the binary tyrosine hydroxylase (TH)-Gal4/UAS-X RNAi Drosophila melanogaster system, we report that Dmp53, basket and drICE ge...
| প্রধান লেখক: | , , |
|---|---|
| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Sociedade Brasileira de Genética
2013-01-01
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| মালা: | Genetics and Molecular Biology |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400020&lng=en&tlng=en |