Dmp53, basket and drICE gene knockdown and polyphenol gallic acid increase life span and locomotor activity in a Drosophila Parkinson's disease model
Understanding the mechanism(s) by which dopaminergic (DAergic) neurons are eroded in Parkinson's disease (PD) is critical for effective therapeutic strategies. By using the binary tyrosine hydroxylase (TH)-Gal4/UAS-X RNAi Drosophila melanogaster system, we report that Dmp53, basket and drICE ge...
| Auteurs principaux: | , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Sociedade Brasileira de Genética
2013-01-01
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| Collection: | Genetics and Molecular Biology |
| Sujets: | |
| Accès en ligne: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400020&lng=en&tlng=en |