The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer
High-risk prostate cancer (PCa), which is defined as PSA >20 ng/mL or Gleason Score (GS) >7 or ≥cT3a, accounts for up to 40% of newly diagnosed cases and carries a significant risk of progression and death. However, the best management approach for patients with high-risk PCa is still unde...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2015-09-01
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| Series: | Journal of Urological Surgery |
| Subjects: | |
| Online Access: | http://jurolsurgery.org/article_9792/The-Role-Of-Radical-Prostatectomy-In-The-Treatment-Of-Patients-With-High-risk-Prostate-Cancer |
| _version_ | 1797912832930480128 |
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| author | Barış Kuzgunbay Özgür Yaycıoğlu |
| author_facet | Barış Kuzgunbay Özgür Yaycıoğlu |
| author_sort | Barış Kuzgunbay |
| collection | DOAJ |
| description | High-risk prostate cancer (PCa), which is defined as PSA >20 ng/mL
or Gleason Score (GS) >7 or ≥cT3a, accounts for up to 40% of newly
diagnosed cases and carries a significant risk of progression and death.
However, the best management approach for patients with high-risk PCa
is still under debate. Recently, radical prostatectomy (RP) with extended
lymphadenectomy (LND) has become popular for the treatment of
high-risk PCa with good prognosis in selected patients in the context
of multimodal approach. However, decision should be made after all
treatments have been discussed by a multidisciplinary team and the
patient should be informed about the likelihood of a multimodal
approach. On the other hand, necessity of sufficient surgical expertise
for RP to keep the level of morbidity acceptable in high-risk PCa patients
should be kept in mind. |
| first_indexed | 2024-04-10T12:02:10Z |
| format | Article |
| id | doaj.art-29a39de5c271447b8f62961e9a489a88 |
| institution | Directory Open Access Journal |
| issn | 2148-9580 |
| language | English |
| last_indexed | 2024-04-10T12:02:10Z |
| publishDate | 2015-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Urological Surgery |
| spelling | doaj.art-29a39de5c271447b8f62961e9a489a882023-02-15T16:16:27ZengGalenos YayineviJournal of Urological Surgery2148-95802015-09-012312012310.4274/jus.515The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate CancerBarış Kuzgunbay0Özgür Yaycıoğlu1Başkent University Faculty of Medicine, Department of Urology, Adana, TurkeyBaşkent University Faculty of Medicine, Department of Urology, Adana, TurkeyHigh-risk prostate cancer (PCa), which is defined as PSA >20 ng/mL or Gleason Score (GS) >7 or ≥cT3a, accounts for up to 40% of newly diagnosed cases and carries a significant risk of progression and death. However, the best management approach for patients with high-risk PCa is still under debate. Recently, radical prostatectomy (RP) with extended lymphadenectomy (LND) has become popular for the treatment of high-risk PCa with good prognosis in selected patients in the context of multimodal approach. However, decision should be made after all treatments have been discussed by a multidisciplinary team and the patient should be informed about the likelihood of a multimodal approach. On the other hand, necessity of sufficient surgical expertise for RP to keep the level of morbidity acceptable in high-risk PCa patients should be kept in mind.http://jurolsurgery.org/article_9792/The-Role-Of-Radical-Prostatectomy-In-The-Treatment-Of-Patients-With-High-risk-Prostate-CancerProstate cancerhigh-risk patientradical prostatectomy |
| spellingShingle | Barış Kuzgunbay Özgür Yaycıoğlu The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer Journal of Urological Surgery Prostate cancer high-risk patient radical prostatectomy |
| title | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer |
| title_full | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer |
| title_fullStr | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer |
| title_full_unstemmed | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer |
| title_short | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer |
| title_sort | role of radical prostatectomy in the treatment of patients with high risk prostate cancer |
| topic | Prostate cancer high-risk patient radical prostatectomy |
| url | http://jurolsurgery.org/article_9792/The-Role-Of-Radical-Prostatectomy-In-The-Treatment-Of-Patients-With-High-risk-Prostate-Cancer |
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