A Review of the Teratogenic Factors Effect on Embryo
Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during developme...
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Format: | Article |
Language: | English |
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Fasa University of Medical Sciences
2016-12-01
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Series: | Journal of Advanced Biomedical Sciences |
Subjects: | |
Online Access: | http://jabs.fums.ac.ir/article-1-1156-en.pdf |
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author | Manzarbanoo Shojaei fard Samira Malekzadeh Mehrdad Shariati |
author_facet | Manzarbanoo Shojaei fard Samira Malekzadeh Mehrdad Shariati |
author_sort | Manzarbanoo Shojaei fard |
collection | DOAJ |
description | Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during development stages and malformation, however a drug may improve general health of the mother, but it might be poisonous for embryo and cause diverse malformation. Since study of embryo health and risk factor in this stage is important, the aim of this review article was the investigation of some types of teratosgens (such as radiation, infectious agents, heat disorders, maternal conditions) and particularly the effect of teratogenic drugs on embryo including some legal drugs (such as acetaminophen, thalidomide, acyclovir, sedatives and anticonvulsants) and illegal drugs (such as nicotine, alcohol, cocaine and marijuana).
Conclusion: In general, teratogens depending on the type and duration of exposure in pregnancyperiod, adversely affect embryo and cause various disorders. A better understanding of these teratogens can contribute to prevent these defects, since many other drugs with similar effects and lower teratogenicity can be used to improve mothers’ health. |
first_indexed | 2024-03-11T23:17:18Z |
format | Article |
id | doaj.art-29a8bf213cda4de9a409170b667b4a0c |
institution | Directory Open Access Journal |
issn | 2228-5105 2783-1523 |
language | English |
last_indexed | 2024-03-11T23:17:18Z |
publishDate | 2016-12-01 |
publisher | Fasa University of Medical Sciences |
record_format | Article |
series | Journal of Advanced Biomedical Sciences |
spelling | doaj.art-29a8bf213cda4de9a409170b667b4a0c2023-09-20T21:22:32ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232016-12-0164426439A Review of the Teratogenic Factors Effect on EmbryoManzarbanoo Shojaei fard0Samira Malekzadeh1Mehrdad Shariati2 Department of Physiology, Fasa University of Medical Sciences, Fasa, Iran Department of Physiology, College of Sciences, Shiraz Branch, Islamic Azad University, Shiraz, Iran Department of Biology, Kazerun Branch, Islamic Azad University, Kazerun, Iran Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during development stages and malformation, however a drug may improve general health of the mother, but it might be poisonous for embryo and cause diverse malformation. Since study of embryo health and risk factor in this stage is important, the aim of this review article was the investigation of some types of teratosgens (such as radiation, infectious agents, heat disorders, maternal conditions) and particularly the effect of teratogenic drugs on embryo including some legal drugs (such as acetaminophen, thalidomide, acyclovir, sedatives and anticonvulsants) and illegal drugs (such as nicotine, alcohol, cocaine and marijuana). Conclusion: In general, teratogens depending on the type and duration of exposure in pregnancyperiod, adversely affect embryo and cause various disorders. A better understanding of these teratogens can contribute to prevent these defects, since many other drugs with similar effects and lower teratogenicity can be used to improve mothers’ health.http://jabs.fums.ac.ir/article-1-1156-en.pdfteratologyteratogenteratogenic drugsembryo development |
spellingShingle | Manzarbanoo Shojaei fard Samira Malekzadeh Mehrdad Shariati A Review of the Teratogenic Factors Effect on Embryo Journal of Advanced Biomedical Sciences teratology teratogen teratogenic drugs embryo development |
title | A Review of the Teratogenic Factors Effect on Embryo |
title_full | A Review of the Teratogenic Factors Effect on Embryo |
title_fullStr | A Review of the Teratogenic Factors Effect on Embryo |
title_full_unstemmed | A Review of the Teratogenic Factors Effect on Embryo |
title_short | A Review of the Teratogenic Factors Effect on Embryo |
title_sort | review of the teratogenic factors effect on embryo |
topic | teratology teratogen teratogenic drugs embryo development |
url | http://jabs.fums.ac.ir/article-1-1156-en.pdf |
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