A Review of the Teratogenic Factors Effect on Embryo

Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during developme...

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Main Authors: Manzarbanoo Shojaei fard, Samira Malekzadeh, Mehrdad Shariati
Format: Article
Language:English
Published: Fasa University of Medical Sciences 2016-12-01
Series:Journal of Advanced Biomedical Sciences
Subjects:
Online Access:http://jabs.fums.ac.ir/article-1-1156-en.pdf
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author Manzarbanoo Shojaei fard
Samira Malekzadeh
Mehrdad Shariati
author_facet Manzarbanoo Shojaei fard
Samira Malekzadeh
Mehrdad Shariati
author_sort Manzarbanoo Shojaei fard
collection DOAJ
description Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during development stages and malformation, however a drug may improve general health of the mother, but it might be poisonous for embryo and cause diverse malformation. Since study of embryo health and risk factor in this stage is important, the aim of this review article was the investigation of some types of teratosgens (such as radiation, infectious agents, heat disorders, maternal conditions) and particularly the effect of teratogenic drugs on embryo including some legal drugs (such as acetaminophen, thalidomide, acyclovir, sedatives and anticonvulsants) and illegal drugs (such as nicotine, alcohol, cocaine and marijuana). Conclusion: In general, teratogens depending on the type and duration of exposure in pregnancyperiod, adversely affect embryo and cause various disorders. A better understanding of these teratogens can contribute to prevent these defects, since many other drugs with similar effects and lower teratogenicity can be used to improve mothers’ health.
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spelling doaj.art-29a8bf213cda4de9a409170b667b4a0c2023-09-20T21:22:32ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232016-12-0164426439A Review of the Teratogenic Factors Effect on EmbryoManzarbanoo Shojaei fard0Samira Malekzadeh1Mehrdad Shariati2 Department of Physiology, Fasa University of Medical Sciences, Fasa, Iran Department of Physiology, College of Sciences, Shiraz Branch, Islamic Azad University, Shiraz, Iran Department of Biology, Kazerun Branch, Islamic Azad University, Kazerun, Iran Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during development stages and malformation, however a drug may improve general health of the mother, but it might be poisonous for embryo and cause diverse malformation. Since study of embryo health and risk factor in this stage is important, the aim of this review article was the investigation of some types of teratosgens (such as radiation, infectious agents, heat disorders, maternal conditions) and particularly the effect of teratogenic drugs on embryo including some legal drugs (such as acetaminophen, thalidomide, acyclovir, sedatives and anticonvulsants) and illegal drugs (such as nicotine, alcohol, cocaine and marijuana). Conclusion: In general, teratogens depending on the type and duration of exposure in pregnancyperiod, adversely affect embryo and cause various disorders. A better understanding of these teratogens can contribute to prevent these defects, since many other drugs with similar effects and lower teratogenicity can be used to improve mothers’ health.http://jabs.fums.ac.ir/article-1-1156-en.pdfteratologyteratogenteratogenic drugsembryo development
spellingShingle Manzarbanoo Shojaei fard
Samira Malekzadeh
Mehrdad Shariati
A Review of the Teratogenic Factors Effect on Embryo
Journal of Advanced Biomedical Sciences
teratology
teratogen
teratogenic drugs
embryo development
title A Review of the Teratogenic Factors Effect on Embryo
title_full A Review of the Teratogenic Factors Effect on Embryo
title_fullStr A Review of the Teratogenic Factors Effect on Embryo
title_full_unstemmed A Review of the Teratogenic Factors Effect on Embryo
title_short A Review of the Teratogenic Factors Effect on Embryo
title_sort review of the teratogenic factors effect on embryo
topic teratology
teratogen
teratogenic drugs
embryo development
url http://jabs.fums.ac.ir/article-1-1156-en.pdf
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