The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children
ABSTRACT CONTEXT AND OBJECTIVE: Helicobacter pylori (H. pylori) is a chronic infectious pathogen with high prevalence. This study investigated the interaction between environmental tobacco exposure and H. pylori infection on the incidence of chronic tonsillitis in Chinese children. DESIGN AND SETT...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Paulista de Medicina
|
| Series: | São Paulo Medical Journal |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802017000100029&lng=en&tlng=en |
| _version_ | 1811239323452833792 |
|---|---|
| author | Chen Li’e Che Juan Jiang Dongying Feng Guiling Zheng Tihua Wang Yanfei |
| author_facet | Chen Li’e Che Juan Jiang Dongying Feng Guiling Zheng Tihua Wang Yanfei |
| author_sort | Chen Li’e |
| collection | DOAJ |
| description | ABSTRACT CONTEXT AND OBJECTIVE: Helicobacter pylori (H. pylori) is a chronic infectious pathogen with high prevalence. This study investigated the interaction between environmental tobacco exposure and H. pylori infection on the incidence of chronic tonsillitis in Chinese children. DESIGN AND SETTING: Cross-sectional study performed in an outpatient clinic in China. METHODS: Pediatric patients with chronic tonsillitis were enrolled. H. pylori infection was determined according to the presence of H. pylori CagA IgG antibodies. Serum cotinine levels and environmental tobacco smoke (ETS) exposure were determined for all participants. RESULTS: There was no significant difference in H. pylori infection between the children with chronic tonsillitis and children free of disease, but there was a significant difference in ETS between the two groups (P = 0.011). We next studied the association between ETS and chronic tonsillitis based on H. pylori infection status. In the patients with H. pylori infection, there was a significant difference in ETS distribution between the chronic tonsillitis and control groups (P = 0.022). Taking the participants without ETS as the reference, multivariate logistic regression analysis showed that those with high ETS had higher susceptibility to chronic tonsillitis (adjusted OR = 2.33; 95% CI: 1.67-3.25; adjusted P < 0.001). However, among those without H. pylori infection, ETS did not predispose towards chronic tonsillitis. CONCLUSION: Our findings suggest that tobacco exposure should be a putative mediator risk factor to chronic tonsillitis among children with H. pylori infection. |
| first_indexed | 2024-04-12T12:58:49Z |
| format | Article |
| id | doaj.art-29acec27a3c84f56bdf0d5a9f080d743 |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-04-12T12:58:49Z |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-29acec27a3c84f56bdf0d5a9f080d7432022-12-22T03:32:14ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94601351293310.1590/1516-3180.2016.023602102016S1516-31802017000100029The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in childrenChen Li’eChe JuanJiang DongyingFeng GuilingZheng TihuaWang YanfeiABSTRACT CONTEXT AND OBJECTIVE: Helicobacter pylori (H. pylori) is a chronic infectious pathogen with high prevalence. This study investigated the interaction between environmental tobacco exposure and H. pylori infection on the incidence of chronic tonsillitis in Chinese children. DESIGN AND SETTING: Cross-sectional study performed in an outpatient clinic in China. METHODS: Pediatric patients with chronic tonsillitis were enrolled. H. pylori infection was determined according to the presence of H. pylori CagA IgG antibodies. Serum cotinine levels and environmental tobacco smoke (ETS) exposure were determined for all participants. RESULTS: There was no significant difference in H. pylori infection between the children with chronic tonsillitis and children free of disease, but there was a significant difference in ETS between the two groups (P = 0.011). We next studied the association between ETS and chronic tonsillitis based on H. pylori infection status. In the patients with H. pylori infection, there was a significant difference in ETS distribution between the chronic tonsillitis and control groups (P = 0.022). Taking the participants without ETS as the reference, multivariate logistic regression analysis showed that those with high ETS had higher susceptibility to chronic tonsillitis (adjusted OR = 2.33; 95% CI: 1.67-3.25; adjusted P < 0.001). However, among those without H. pylori infection, ETS did not predispose towards chronic tonsillitis. CONCLUSION: Our findings suggest that tobacco exposure should be a putative mediator risk factor to chronic tonsillitis among children with H. pylori infection.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802017000100029&lng=en&tlng=enHelicobacter pyloriTonsilitePoluição por fumaça de tabacoCriançasInfecção |
| spellingShingle | Chen Li’e Che Juan Jiang Dongying Feng Guiling Zheng Tihua Wang Yanfei The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children São Paulo Medical Journal Helicobacter pylori Tonsilite Poluição por fumaça de tabaco Crianças Infecção |
| title | The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children |
| title_full | The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children |
| title_fullStr | The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children |
| title_full_unstemmed | The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children |
| title_short | The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children |
| title_sort | role of environmental tobacco exposure and helicobacter pylori infection in the risk of chronic tonsillitis in children |
| topic | Helicobacter pylori Tonsilite Poluição por fumaça de tabaco Crianças Infecção |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802017000100029&lng=en&tlng=en |
| work_keys_str_mv | AT chenlie theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT chejuan theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT jiangdongying theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT fengguiling theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT zhengtihua theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT wangyanfei theroleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT chenlie roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT chejuan roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT jiangdongying roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT fengguiling roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT zhengtihua roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren AT wangyanfei roleofenvironmentaltobaccoexposureandhelicobacterpyloriinfectionintheriskofchronictonsillitisinchildren |