Lumican promotes joint fibrosis through TGF‐β signaling

Lumican promotes joint fibrosis through TGF‐β signaling

Joint contracture (also known as arthrofibrosis) is a fibrotic joint disorder characterized by excessive collagen production to form fibrotic scar tissue and adhesions within joint capsules. This can severely affect day‐to‐day activities and quality of life because of a restricted range of motion in...

Full description

Bibliographic Details
Main Authors: Dahai Xiao, Tangzhao Liang, Ze Zhuang, Ronghan He, Jianhua Ren, Shihai Jiang, Lei Zhu, Kun Wang, Dehai Shi
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:FEBS Open Bio
Subjects:
joint capsule synovial fibroblasts
joint contracture
lumican
myofibroblast activation
TGF‐β
Online Access:https://doi.org/10.1002/2211-5463.12974

Similar Items

Similar Items