Overexpression of DAPK1 and Beclin1 under oxygen and glucose deprivation conditions promotes excessive autophagy and apoptosis in A549 cells

Overexpression of DAPK1 and Beclin1 under oxygen and glucose deprivation conditions promotes excessive autophagy and apoptosis in A549 cells

Abstract In this study, we aimed to determine the specific roles of death‐associated protein kinase 1 (DAPK1) and Beclin1 in non‐small cell lung cancer (NSCLC) under oxygen and glucose deprivation (OGD). We found that OGD caused most cells to shrink, aggregate, and produce many vacuoles in the cytop...

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Bibliographic Details
Main Authors: Linlin Wu, Wenxue Sun, Dehua Liao, Yujin Guo, Qingying Si, Dadi Xie, Pei Jiang
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:MedComm – Oncology
Subjects:
apoptosis
autophagy
Beclin1
DAPK1
non‐small cell lung cancer
oxygen and glucose deprivation
Online Access:https://doi.org/10.1002/mog2.30

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