Pediatric Systemic Lupus Erythematous in COVID-19 Era
Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increa...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/2/272 |
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| author | Ancuta Lupu Ingrith Crenguta Miron Cristina Gavrilovici Anca Adam Raileanu Iuliana Magdalena Starcea Ileana Ioniuc Alice Azoicai Adriana Mocanu Lacramioara Ionela Butnariu Felicia Dragan Vasile Valeriu Lupu |
| author_facet | Ancuta Lupu Ingrith Crenguta Miron Cristina Gavrilovici Anca Adam Raileanu Iuliana Magdalena Starcea Ileana Ioniuc Alice Azoicai Adriana Mocanu Lacramioara Ionela Butnariu Felicia Dragan Vasile Valeriu Lupu |
| author_sort | Ancuta Lupu |
| collection | DOAJ |
| description | Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increase the risk of severe COVID-19 and poor outcomes of the disease in pediatric systemic lupus erythematosus (SLE) patients. The aim of this review is to obtain a better understanding of the existing link between this new viral infection and pediatric lupus. We have analyzed the characteristics of newly diagnosed cases of pediatric SLE following COVID-19 which have been reported in the literature and which describe the impact that COVID-19 has on patients already suffering with pediatric SLE. |
| first_indexed | 2024-03-11T08:00:28Z |
| format | Article |
| id | doaj.art-29b57a60a7e141c0912debfe6baf89ed |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T08:00:28Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-29b57a60a7e141c0912debfe6baf89ed2023-11-16T23:46:46ZengMDPI AGViruses1999-49152023-01-0115227210.3390/v15020272Pediatric Systemic Lupus Erythematous in COVID-19 EraAncuta Lupu0Ingrith Crenguta Miron1Cristina Gavrilovici2Anca Adam Raileanu3Iuliana Magdalena Starcea4Ileana Ioniuc5Alice Azoicai6Adriana Mocanu7Lacramioara Ionela Butnariu8Felicia Dragan9Vasile Valeriu Lupu10Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaMother and Child Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, RomaniaPediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaPediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increase the risk of severe COVID-19 and poor outcomes of the disease in pediatric systemic lupus erythematosus (SLE) patients. The aim of this review is to obtain a better understanding of the existing link between this new viral infection and pediatric lupus. We have analyzed the characteristics of newly diagnosed cases of pediatric SLE following COVID-19 which have been reported in the literature and which describe the impact that COVID-19 has on patients already suffering with pediatric SLE.https://www.mdpi.com/1999-4915/15/2/272systemic lupus erythematosusCOVID-19vaccinechild |
| spellingShingle | Ancuta Lupu Ingrith Crenguta Miron Cristina Gavrilovici Anca Adam Raileanu Iuliana Magdalena Starcea Ileana Ioniuc Alice Azoicai Adriana Mocanu Lacramioara Ionela Butnariu Felicia Dragan Vasile Valeriu Lupu Pediatric Systemic Lupus Erythematous in COVID-19 Era Viruses systemic lupus erythematosus COVID-19 vaccine child |
| title | Pediatric Systemic Lupus Erythematous in COVID-19 Era |
| title_full | Pediatric Systemic Lupus Erythematous in COVID-19 Era |
| title_fullStr | Pediatric Systemic Lupus Erythematous in COVID-19 Era |
| title_full_unstemmed | Pediatric Systemic Lupus Erythematous in COVID-19 Era |
| title_short | Pediatric Systemic Lupus Erythematous in COVID-19 Era |
| title_sort | pediatric systemic lupus erythematous in covid 19 era |
| topic | systemic lupus erythematosus COVID-19 vaccine child |
| url | https://www.mdpi.com/1999-4915/15/2/272 |
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