Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India
Abstract Background Deltamethrin 62.5 polymer-enhanced suspension concentrate (SC-PE) is one of the World Health Organization-approved insecticides for indoor residual spraying and was recommended to evaluate its residual activity for determination of appropriate spray cycles in different eco-epidem...
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | Malaria Journal |
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| Online Access: | https://doi.org/10.1186/s12936-020-3112-4 |
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| author | Sudhansu Sekhar Sahu Sonia Thankachy Smrutidhara Dash Krishnamoorthy Nallan Subramanian Swaminathan Gunasekaran Kasinathan Jambulingam Purushothaman |
| author_facet | Sudhansu Sekhar Sahu Sonia Thankachy Smrutidhara Dash Krishnamoorthy Nallan Subramanian Swaminathan Gunasekaran Kasinathan Jambulingam Purushothaman |
| author_sort | Sudhansu Sekhar Sahu |
| collection | DOAJ |
| description | Abstract Background Deltamethrin 62.5 polymer-enhanced suspension concentrate (SC-PE) is one of the World Health Organization-approved insecticides for indoor residual spraying and was recommended to evaluate its residual activity for determination of appropriate spray cycles in different eco-epidemiologic settings. In the current study, efficacy of deltamethrin 62.5 SC-PE was evaluated against vectors of malaria and its impact on malaria incidence in a Plasmodium falciparum hyper-endemic area in Koraput district, Odisha State, India. Methods The trial had two comparable arms, arm 1 with residual spraying of deltamethrin 62.5 SC-PE and arm 2 with deltamethrin 2.5% WP (positive control). Comparative assessment of the impact of each intervention arm on entomological (density, parity, infection and human blood index), epidemiological (malaria incidence) parameters, residual efficacy and adverse effects were evaluated. Results Both the arms were comparable in terms of entomological and epidemiological parameters. While, deltamethrin 62.5 SC-PE was found to be effective for 150 days in mud and wood surfaces and 157 days in cement surfaces; deltamethrin 2.5% was effective only for 105 days on mud surfaces and 113 days on cement and wood surfaces. Conclusions Deltamethrin 62.5 SC-PE had prolonged killing effectiveness up to 5 months. Hence, one round of IRS with deltamethrin 62.5 SC-PE would be sufficient to cover two existing malaria peak transmission seasons (July–August and October–November) in many parts of India. |
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| format | Article |
| id | doaj.art-29b6a54be9f04ec2b31a47e786421406 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-17T06:32:33Z |
| publishDate | 2020-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-29b6a54be9f04ec2b31a47e7864214062022-12-21T22:00:06ZengBMCMalaria Journal1475-28752020-01-0119111510.1186/s12936-020-3112-4Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in IndiaSudhansu Sekhar Sahu0Sonia Thankachy1Smrutidhara Dash2Krishnamoorthy Nallan3Subramanian Swaminathan4Gunasekaran Kasinathan5Jambulingam Purushothaman6Indian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreIndian Council of Medical Research-Vector Control Research CentreAbstract Background Deltamethrin 62.5 polymer-enhanced suspension concentrate (SC-PE) is one of the World Health Organization-approved insecticides for indoor residual spraying and was recommended to evaluate its residual activity for determination of appropriate spray cycles in different eco-epidemiologic settings. In the current study, efficacy of deltamethrin 62.5 SC-PE was evaluated against vectors of malaria and its impact on malaria incidence in a Plasmodium falciparum hyper-endemic area in Koraput district, Odisha State, India. Methods The trial had two comparable arms, arm 1 with residual spraying of deltamethrin 62.5 SC-PE and arm 2 with deltamethrin 2.5% WP (positive control). Comparative assessment of the impact of each intervention arm on entomological (density, parity, infection and human blood index), epidemiological (malaria incidence) parameters, residual efficacy and adverse effects were evaluated. Results Both the arms were comparable in terms of entomological and epidemiological parameters. While, deltamethrin 62.5 SC-PE was found to be effective for 150 days in mud and wood surfaces and 157 days in cement surfaces; deltamethrin 2.5% was effective only for 105 days on mud surfaces and 113 days on cement and wood surfaces. Conclusions Deltamethrin 62.5 SC-PE had prolonged killing effectiveness up to 5 months. Hence, one round of IRS with deltamethrin 62.5 SC-PE would be sufficient to cover two existing malaria peak transmission seasons (July–August and October–November) in many parts of India.https://doi.org/10.1186/s12936-020-3112-4Anopheles culicifaciesAnopheles fluviatilisDeltamethrin 62.5 SC-PEIndiaIndoor residual spraying |
| spellingShingle | Sudhansu Sekhar Sahu Sonia Thankachy Smrutidhara Dash Krishnamoorthy Nallan Subramanian Swaminathan Gunasekaran Kasinathan Jambulingam Purushothaman Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India Malaria Journal Anopheles culicifacies Anopheles fluviatilis Deltamethrin 62.5 SC-PE India Indoor residual spraying |
| title | Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India |
| title_full | Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India |
| title_fullStr | Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India |
| title_full_unstemmed | Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India |
| title_short | Evaluation of long-lasting indoor residual spraying of deltamethrin 62.5 SC-PE against malaria vectors in India |
| title_sort | evaluation of long lasting indoor residual spraying of deltamethrin 62 5 sc pe against malaria vectors in india |
| topic | Anopheles culicifacies Anopheles fluviatilis Deltamethrin 62.5 SC-PE India Indoor residual spraying |
| url | https://doi.org/10.1186/s12936-020-3112-4 |
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