The importance of cache domains in α2δ proteins and the basis for their gabapentinoid selectivity

ABSTRACTIn this hybrid review, we have first collected and reviewed available information on the structure and function of the enigmatic cache domains in α2δ proteins. These are organized into two double cache (dCache_1) domains, and they are present in all α2δ proteins. We have also included new da...

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Bibliographic Details
Main Authors: Karen M Page, Vadim M Gumerov, Shehrazade Dahimene, Igor B Zhulin, Annette C Dolphin
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2023.2167563

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