Tuberculosis of the prostate and urethra: A review
Genitourinary tuberculosis contributes to 10-14% of extrapulmonary tuberculosis and is a major health problem in India. Prostate tuberculosis is uncommon and is usually found incidentally following transurethral resection. The most common mode of involvement is hematogenous, though descending infect...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2008-01-01
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| Series: | Indian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2008;volume=24;issue=3;spage=388;epage=391;aulast=Gupta |
| _version_ | 1811322395908112384 |
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| author | Nitin Gupta A K Mandal S K Singh |
| author_facet | Nitin Gupta A K Mandal S K Singh |
| author_sort | Nitin Gupta |
| collection | DOAJ |
| description | Genitourinary tuberculosis contributes to 10-14% of extrapulmonary tuberculosis and is a major health problem in India. Prostate tuberculosis is uncommon and is usually found incidentally following transurethral resection. The most common mode of involvement is hematogenous, though descending infection and direct intracanalicular extension is known. Predisposing factors include prior tubercular infection, immuno-compromised status, previous BCG therapy. The presentation is diffuse caseating epitheloid cell granulomas, which can be confirmed by prostate biopsy. Urine PCR has good sensitivity (95.5%) and specificity ( 98.12%) in diagnosis. Imaging techniques like TRUS and CT/MRI also allow good visualization of the lesion and its extension. Urethral tuberculosis is very rare and is usually secondary to upper tract or genital tuberculosis. The presentation may be acute urethritis or chronic stricture or fistulae. The treatment of choice is chemotherapy with 3-4 anti tubercular drugs for initial 6-12 weeks and later 2 drugs for additional 3-6 months. Surgery is usually reserved for cases where chemotherapy fails and is done after 4-6 weeks of ATT. With a high index of suspicion it may be possible to diagnose a larger number of cases of prostatic and urethral tuberculosis especially in this country where tuberculosis is almost endemic. |
| first_indexed | 2024-04-13T13:35:36Z |
| format | Article |
| id | doaj.art-29b86c60c8074cb684881e1202dc03c4 |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-04-13T13:35:36Z |
| publishDate | 2008-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-29b86c60c8074cb684881e1202dc03c42022-12-22T02:44:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242008-01-0124338839110.4103/0970-1591.42623Tuberculosis of the prostate and urethra: A reviewNitin GuptaA K MandalS K SinghGenitourinary tuberculosis contributes to 10-14% of extrapulmonary tuberculosis and is a major health problem in India. Prostate tuberculosis is uncommon and is usually found incidentally following transurethral resection. The most common mode of involvement is hematogenous, though descending infection and direct intracanalicular extension is known. Predisposing factors include prior tubercular infection, immuno-compromised status, previous BCG therapy. The presentation is diffuse caseating epitheloid cell granulomas, which can be confirmed by prostate biopsy. Urine PCR has good sensitivity (95.5%) and specificity ( 98.12%) in diagnosis. Imaging techniques like TRUS and CT/MRI also allow good visualization of the lesion and its extension. Urethral tuberculosis is very rare and is usually secondary to upper tract or genital tuberculosis. The presentation may be acute urethritis or chronic stricture or fistulae. The treatment of choice is chemotherapy with 3-4 anti tubercular drugs for initial 6-12 weeks and later 2 drugs for additional 3-6 months. Surgery is usually reserved for cases where chemotherapy fails and is done after 4-6 weeks of ATT. With a high index of suspicion it may be possible to diagnose a larger number of cases of prostatic and urethral tuberculosis especially in this country where tuberculosis is almost endemic.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2008;volume=24;issue=3;spage=388;epage=391;aulast=GuptaGenitourinarygranulomatousinfectionprostateraretuberculosisurethra |
| spellingShingle | Nitin Gupta A K Mandal S K Singh Tuberculosis of the prostate and urethra: A review Indian Journal of Urology Genitourinary granulomatous infection prostate rare tuberculosis urethra |
| title | Tuberculosis of the prostate and urethra: A review |
| title_full | Tuberculosis of the prostate and urethra: A review |
| title_fullStr | Tuberculosis of the prostate and urethra: A review |
| title_full_unstemmed | Tuberculosis of the prostate and urethra: A review |
| title_short | Tuberculosis of the prostate and urethra: A review |
| title_sort | tuberculosis of the prostate and urethra a review |
| topic | Genitourinary granulomatous infection prostate rare tuberculosis urethra |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2008;volume=24;issue=3;spage=388;epage=391;aulast=Gupta |
| work_keys_str_mv | AT nitingupta tuberculosisoftheprostateandurethraareview AT akmandal tuberculosisoftheprostateandurethraareview AT sksingh tuberculosisoftheprostateandurethraareview |