Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway.
Inhibition of VEGFR2 activity has been proposed as an important strategy for the clinical treatment of hepatocellular carcinoma (HCC). In this study, we identified corosolic acid (CA), which exists in the root of Actinidia chinensis, as having a significant anti-cancer effect on HCC cells. We found...
Main Authors: | Chung-Yu Ku, Ying-Ren Wang, Hsuan-Yuan Lin, Shao-Chun Lu, Jung-Yaw Lin |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4433267?pdf=render |
Similar Items
-
Arecoline Promotes Migration of A549 Lung Cancer Cells through Activating the EGFR/Src/FAK Pathway
by: Chih-Hsiang Chang, et al.
Published: (2019-03-01) -
Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration
by: Thanasekaran Jayakumar, et al.
Published: (2021-12-01) -
Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.
by: Guo-Sheng Wu, et al.
Published: (2013-01-01) -
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway
by: Caihua Dong, et al.
Published: (2021-09-01) -
Caffeine Inhibits Migration in Glioma Cells through the ROCK-FAK Pathway
by: Ying Chen, et al.
Published: (2014-06-01)