Amiodarone inhibits apamin-sensitive potassium currents.

Amiodarone inhibits apamin-sensitive potassium currents.

Apamin sensitive potassium current (I KAS), carried by the type 2 small conductance Ca(2+)-activated potassium (SK2) channels, plays an important role in post-shock action potential duration (APD) shortening and recurrent spontaneous ventricular fibrillation (VF) in failing ventricles.To test the hy...

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Bibliographic Details
Main Authors: Isik Turker, Chih-Chieh Yu, Po-Cheng Chang, Zhenhui Chen, Yoshiro Sohma, Shien-Fong Lin, Peng-Sheng Chen, Tomohiko Ai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726612?pdf=render

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