Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019
<p><strong>Background</strong>: non-opioid analgesics are the mostly used drugs for pain relief and inflammation worldwide. However, this benefit is closely associated with adverse reactions.</p><p><strong>Objective</strong>: to characterize the adverse reac...
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| Format: | Article |
| Language: | Spanish |
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Universidad de Ciencias Médicas de Las Tunas
2020-11-01
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| Series: | Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta |
| Subjects: | |
| Online Access: | http://revzoilomarinello.sld.cu/index.php/zmv/article/view/2490 |
| _version_ | 1818655424593788928 |
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| author | Maité Rúa-del-Toro Lilisbeth de la Caridad Benitez-Rojas Sahily de la Caridad Rojas-Pérez Yordanis Pupo-Pérez |
| author_facet | Maité Rúa-del-Toro Lilisbeth de la Caridad Benitez-Rojas Sahily de la Caridad Rojas-Pérez Yordanis Pupo-Pérez |
| author_sort | Maité Rúa-del-Toro |
| collection | DOAJ |
| description | <p><strong>Background</strong>: non-opioid analgesics are the mostly used drugs for pain relief and inflammation worldwide. However, this benefit is closely associated with adverse reactions.</p><p><strong>Objective</strong>: to characterize the adverse reactions to non-opioid analgesics registered at the database of pharmacovigilance of the province of Las Tunas, from 2017 to the first semester of 2019.</p><p><strong>Methods</strong>: a cross-sectional, descriptive, observational study was carried out at the place and during the period herein declared. The university consisted of the 1711 registers of the main adverse reactions conducted in the study period and the sample included 180 corresponding to non-opioid analgesics. Descriptive statistics was used for the analysis of data.</p><p><strong>Results</strong>: the highest number of registers were related to the female sex with 116 reports (64,4 %) and the 41 to 60 age group with 68 (37,8 %). The adverse reactions that predominated were the frequent ones, 68 registers (37,8 %); according to severity there was a higher notification of the mild ones with 98 reports (54,4 %) and according to causality the probable ones prevailed with 137 registers (76,7 %). The mostly affected organ system was the skin, 84 registers (46,7 %), being cutaneous eruption, with 18 registers (10 %), the most registered one within the system and in general among all reactions. The drug with most registers of adverse reactions was metamizole, 56 registers (31,1 %).</p><p><strong>Conclusions</strong>: the study could characterize the notifications of adverse reactions to non-opioid analgesics in Las Tunas.</p> |
| first_indexed | 2024-12-17T03:09:28Z |
| format | Article |
| id | doaj.art-29c363ccc80f4187926937e583fc07ed |
| institution | Directory Open Access Journal |
| issn | 1029-3027 |
| language | Spanish |
| last_indexed | 2024-12-17T03:09:28Z |
| publishDate | 2020-11-01 |
| publisher | Universidad de Ciencias Médicas de Las Tunas |
| record_format | Article |
| series | Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta |
| spelling | doaj.art-29c363ccc80f4187926937e583fc07ed2022-12-21T22:05:51ZspaUniversidad de Ciencias Médicas de Las TunasRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta1029-30272020-11-014561109Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019Maité Rúa-del-Toro0Lilisbeth de la Caridad Benitez-Rojas1Sahily de la Caridad Rojas-Pérez2Yordanis Pupo-Pérez3Hospital General Docente “Dr. Ernesto Guevara de la Serna”. Las Tunas. Universidad de Ciencias Médicas de Las Tunas. Facultad de Ciencias Médicas “Dr. Zoilo Enrique Marinello Vidaurreta”. Las Tunas.Universidad de Ciencias Médicas de Las Tunas. Facultad de Ciencias Médicas “Dr. Zoilo Enrique Marinello Vidaurreta”. Las Tunas.Universidad de Ciencias Médicas de Las Tunas. Facultad de Ciencias Médicas “Dr. Zoilo Enrique Marinello Vidaurreta”. Las Tunas.Dirección Municipal de Salud. Las Tunas. Universidad de Ciencias Médicas de Las Tunas. Facultad de Ciencias Médicas “Dr. Zoilo Enrique Marinello Vidaurreta”. Las Tunas.<p><strong>Background</strong>: non-opioid analgesics are the mostly used drugs for pain relief and inflammation worldwide. However, this benefit is closely associated with adverse reactions.</p><p><strong>Objective</strong>: to characterize the adverse reactions to non-opioid analgesics registered at the database of pharmacovigilance of the province of Las Tunas, from 2017 to the first semester of 2019.</p><p><strong>Methods</strong>: a cross-sectional, descriptive, observational study was carried out at the place and during the period herein declared. The university consisted of the 1711 registers of the main adverse reactions conducted in the study period and the sample included 180 corresponding to non-opioid analgesics. Descriptive statistics was used for the analysis of data.</p><p><strong>Results</strong>: the highest number of registers were related to the female sex with 116 reports (64,4 %) and the 41 to 60 age group with 68 (37,8 %). The adverse reactions that predominated were the frequent ones, 68 registers (37,8 %); according to severity there was a higher notification of the mild ones with 98 reports (54,4 %) and according to causality the probable ones prevailed with 137 registers (76,7 %). The mostly affected organ system was the skin, 84 registers (46,7 %), being cutaneous eruption, with 18 registers (10 %), the most registered one within the system and in general among all reactions. The drug with most registers of adverse reactions was metamizole, 56 registers (31,1 %).</p><p><strong>Conclusions</strong>: the study could characterize the notifications of adverse reactions to non-opioid analgesics in Las Tunas.</p>http://revzoilomarinello.sld.cu/index.php/zmv/article/view/2490asthma, aspirin-inducedanalgesics, non-narcoticpharmacovigilancedrug-related side effects and adverse reactions. |
| spellingShingle | Maité Rúa-del-Toro Lilisbeth de la Caridad Benitez-Rojas Sahily de la Caridad Rojas-Pérez Yordanis Pupo-Pérez Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta asthma, aspirin-induced analgesics, non-narcotic pharmacovigilance drug-related side effects and adverse reactions. |
| title | Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 |
| title_full | Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 |
| title_fullStr | Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 |
| title_full_unstemmed | Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 |
| title_short | Adverse reactions to non-opioid analgesics notified in Las Tunas, 2017 though the first semester of 2019 |
| title_sort | adverse reactions to non opioid analgesics notified in las tunas 2017 though the first semester of 2019 |
| topic | asthma, aspirin-induced analgesics, non-narcotic pharmacovigilance drug-related side effects and adverse reactions. |
| url | http://revzoilomarinello.sld.cu/index.php/zmv/article/view/2490 |
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