Single-cell landscape of immune cells during the progression from HBV infection to HBV cirrhosis and HBV-associated hepatocellular carcinoma

Single-cell landscape of immune cells during the progression from HBV infection to HBV cirrhosis and HBV-associated hepatocellular carcinoma

IntroductionImmune cells play crucial roles in the development of chronic hepatitis B virus (HBV) infection, leading to cirrhosis and hepatocellular carcinoma (HCC). However, their functions at different disease stages are not fully understood.MethodsIn this study, we used single-cell RNA sequencing...

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Bibliographic Details
Main Authors: Qingquan Bai, Runyang Li, Xiao He, Xiaoting Hong, Ying Yan, Zhengyang Zhao, Han Lin, Frank Tacke, Cornelius Engelmann, Tianhui Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
hepatitis B
cirrhosis
HBV infection
hepatocellular carcinoma
scRNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1320414/full

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