Interaction between NSCLC Cells, CD8<sup>+</sup> T-Cells and Immune Checkpoint Inhibitors Potentiates Coagulation and Promotes Metabolic Remodeling—New Cues on CAT-VTE

Interaction between NSCLC Cells, CD8<sup>+</sup> T-Cells and Immune Checkpoint Inhibitors Potentiates Coagulation and Promotes Metabolic Remodeling—New Cues on CAT-VTE

Background: Cancer-associated thrombosis (CAT) and venous thromboembolism (VTE) are frequent cancer-related complications associated with high mortality; thus, this urges the identification of predictive markers. Immune checkpoint inhibitors (ICIs) used in cancer immunotherapy allow T-cell activatio...

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Bibliographic Details
Main Authors: Catarina Freitas-Dias, Filipe Gonçalves, Filipa Martins, Isabel Lemos, Luís G. Gonçalves, Jacinta Serpa
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
cancer-associated thrombosis (CAT)
venous thromboembolism (VTE)
immune checkpoint inhibitors (ICIs)
non-small cell lung cancer (NSCLC)
metabolic remodeling
tissue factor (TF)
Online Access:https://www.mdpi.com/2073-4409/13/4/305

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