Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review

Abstract Objective To conduct a systematic review of literature on use and efficacy of cognitive-behavioral therapy (CBT) for treatment of treatment-resistant depression in adults and adolescents. Methods We performed a systematic review according to the Prisma Guidelines of literature indexed o...

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Main Authors: Stephanie Zakhour, Antonio E. Nardi, Michelle Levitan, Jose Carlos Appolinario
Format: Article
Language:English
Published: Associação de Psiquiatria do Rio Grande do Sul
Series:Trends in Psychiatry and Psychotherapy
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892020000100092&lng=en&tlng=en
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author Stephanie Zakhour
Antonio E. Nardi
Michelle Levitan
Jose Carlos Appolinario
author_facet Stephanie Zakhour
Antonio E. Nardi
Michelle Levitan
Jose Carlos Appolinario
author_sort Stephanie Zakhour
collection DOAJ
description Abstract Objective To conduct a systematic review of literature on use and efficacy of cognitive-behavioral therapy (CBT) for treatment of treatment-resistant depression in adults and adolescents. Methods We performed a systematic review according to the Prisma Guidelines of literature indexed on the PubMed, SciELO, Psychiatry Online, Scopus, PsycArticles, Science Direct and the Journal of Medical Case Reports databases. Randomized controlled trials, open studies and case reports were included in the review. Results The searches returned a total of 1,580 articles, published from 1985 to 2017. After applying the inclusion criteria, 17 articles were selected, their complete texts were read and 8 were included in this review. Four of these studies were randomized controlled trials with adults, one of which covered a post-study follow-up period; two were randomized controlled trials with adolescents, one of which presented follow-up data; one was an open study; and one was a case report. The studies provide good quality and robust evidence on the topic addressed. Conclusions A combination of CBT with pharmacotherapy for treatment-resistant patients shows a decrease in depressive symptoms. CBT can be an effective type of therapy for adults and adolescents with treatment-resistant depression.
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spelling doaj.art-29cffc8df0d843df96ddb968b848a2c52022-12-21T23:55:43ZengAssociação de Psiquiatria do Rio Grande do SulTrends in Psychiatry and Psychotherapy2237-60892238-00194219210110.1590/2237-6089-2019-0033S2237-60892020000100092Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic reviewStephanie ZakhourAntonio E. NardiMichelle LevitanJose Carlos AppolinarioAbstract Objective To conduct a systematic review of literature on use and efficacy of cognitive-behavioral therapy (CBT) for treatment of treatment-resistant depression in adults and adolescents. Methods We performed a systematic review according to the Prisma Guidelines of literature indexed on the PubMed, SciELO, Psychiatry Online, Scopus, PsycArticles, Science Direct and the Journal of Medical Case Reports databases. Randomized controlled trials, open studies and case reports were included in the review. Results The searches returned a total of 1,580 articles, published from 1985 to 2017. After applying the inclusion criteria, 17 articles were selected, their complete texts were read and 8 were included in this review. Four of these studies were randomized controlled trials with adults, one of which covered a post-study follow-up period; two were randomized controlled trials with adolescents, one of which presented follow-up data; one was an open study; and one was a case report. The studies provide good quality and robust evidence on the topic addressed. Conclusions A combination of CBT with pharmacotherapy for treatment-resistant patients shows a decrease in depressive symptoms. CBT can be an effective type of therapy for adults and adolescents with treatment-resistant depression.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892020000100092&lng=en&tlng=enterapia cognitivo-comportamentaltranstorno depressivo maiortranstorno depressivo resistente a tratamento
spellingShingle Stephanie Zakhour
Antonio E. Nardi
Michelle Levitan
Jose Carlos Appolinario
Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
Trends in Psychiatry and Psychotherapy
terapia cognitivo-comportamental
transtorno depressivo maior
transtorno depressivo resistente a tratamento
title Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
title_full Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
title_fullStr Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
title_full_unstemmed Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
title_short Cognitive-behavioral therapy for treatment-resistant depression in adults and adolescents: a systematic review
title_sort cognitive behavioral therapy for treatment resistant depression in adults and adolescents a systematic review
topic terapia cognitivo-comportamental
transtorno depressivo maior
transtorno depressivo resistente a tratamento
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892020000100092&lng=en&tlng=en
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