Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting
Background and purpose: The present study aimed at investigating the effect of a period of cardiac rehabilitation program with consumption of vitamin D on NO, ET1, VEGF, anxiety, and depression levels in cardiac patients after coronary artery bypass graft surgery )CABG(. Materials and methods: A cli...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2019-02-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-11165-en.html |
| _version_ | 1797943835993571328 |
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| author | Bahareh Samadi Parvin Farzanegi Zahra Madani |
| author_facet | Bahareh Samadi Parvin Farzanegi Zahra Madani |
| author_sort | Bahareh Samadi |
| collection | DOAJ |
| description | Background and purpose: The present study aimed at investigating the effect of a period of cardiac rehabilitation program with consumption of vitamin D on NO, ET1, VEGF, anxiety, and depression levels in cardiac patients after coronary artery bypass graft surgery )CABG(.
Materials and methods: A clinical trial was conducted in 32 cardiac patients undergoing CABG surgery in Sari Fatemeh Zahra Hospital. The subjects were randomly divided into four groups including control, vitamin D, exercise, and exercise-vitamin D. The training program included aerobic exercises (70-85% maximum heart rate/60-85 min) followed by strength exercises in three sets with 10 repetitions (20-60% of maximum repetition for 6 weeks/3 sessions per week). The levels of NO, ET1, VEGF anxiety, and depression were investigated before and after 6 weeks. Data were analyzed using correlated t-test and two-way ANOVA test.
Results: In the exercise, vitamin D, and exercise-vitamin D groups, the levels of NO and VEGF increased significantly, but ET1 level showed a significant decrease. Furthermore, significant reductions were seen in anxiety and depression levels in all groups (P<0.05).
Conclusion: Current study showed vitamin D and exercise-vitamin D could improve the levels of NO, ET1, VEGF, anxiety, and depression in cardiac patients after CABG surgery. Nevertheless, exercise-vitamin D was more effective in improving the NO, ET1, VEGF, anxiety, and depression levels. |
| first_indexed | 2024-04-10T20:30:25Z |
| format | Article |
| id | doaj.art-29d1bc9ccf054deb96399a27bbe41a0f |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:30:25Z |
| publishDate | 2019-02-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-29d1bc9ccf054deb96399a27bbe41a0f2023-01-25T06:58:45ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-02-01281695264Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass GraftingBahareh Samadi0Parvin Farzanegi1Zahra Madani2 MSc in Exercise Physiology, School of Humanities, Islamic Azad University, Sari Branch, Sari, Iran Associate Professor, School of Humanities, Islamic Azad University Sari Branch, Sari, Iran Assistant Professor, Department of Sport Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: The present study aimed at investigating the effect of a period of cardiac rehabilitation program with consumption of vitamin D on NO, ET1, VEGF, anxiety, and depression levels in cardiac patients after coronary artery bypass graft surgery )CABG(. Materials and methods: A clinical trial was conducted in 32 cardiac patients undergoing CABG surgery in Sari Fatemeh Zahra Hospital. The subjects were randomly divided into four groups including control, vitamin D, exercise, and exercise-vitamin D. The training program included aerobic exercises (70-85% maximum heart rate/60-85 min) followed by strength exercises in three sets with 10 repetitions (20-60% of maximum repetition for 6 weeks/3 sessions per week). The levels of NO, ET1, VEGF anxiety, and depression were investigated before and after 6 weeks. Data were analyzed using correlated t-test and two-way ANOVA test. Results: In the exercise, vitamin D, and exercise-vitamin D groups, the levels of NO and VEGF increased significantly, but ET1 level showed a significant decrease. Furthermore, significant reductions were seen in anxiety and depression levels in all groups (P<0.05). Conclusion: Current study showed vitamin D and exercise-vitamin D could improve the levels of NO, ET1, VEGF, anxiety, and depression in cardiac patients after CABG surgery. Nevertheless, exercise-vitamin D was more effective in improving the NO, ET1, VEGF, anxiety, and depression levels.http://jmums.mazums.ac.ir/article-1-11165-en.htmlcardiac rehabilitationvitamin dcoronary artery bypass graft surgeryvegfet1no |
| spellingShingle | Bahareh Samadi Parvin Farzanegi Zahra Madani Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting Journal of Mazandaran University of Medical Sciences cardiac rehabilitation vitamin d coronary artery bypass graft surgery vegf et1 no |
| title | Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting |
| title_full | Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting |
| title_fullStr | Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting |
| title_full_unstemmed | Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting |
| title_short | Cardiac Rehabilitation Program and Vitamin D Supplement on NO, ET1, VEGF, Anxiety, and Depression Levels in Cardiac Patients after Coronary Artery Bypass Grafting |
| title_sort | cardiac rehabilitation program and vitamin d supplement on no et1 vegf anxiety and depression levels in cardiac patients after coronary artery bypass grafting |
| topic | cardiac rehabilitation vitamin d coronary artery bypass graft surgery vegf et1 no |
| url | http://jmums.mazums.ac.ir/article-1-11165-en.html |
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