Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer

Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer

Colorectal cancer is the third most diagnosed cancer and the second leading cause of cancer mortality worldwide, highlighting an urgent need for new therapeutic options and combination strategies for patients. The orchestration of potent T cell responses against human cancers is necessary for effect...

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Bibliographic Details
Main Authors: Mathieu J. F. Crupi, Zaid Taha, Thijs J. A. Janssen, Julia Petryk, Stephen Boulton, Nouf Alluqmani, Anna Jirovec, Omar Kassas, Sarwat T. Khan, Sydney Vallati, Emily Lee, Ben Zhen Huang, Michael Huh, Larissa Pikor, Xiaohong He, Ricardo Marius, Bradley Austin, Jessie Duong, Adrian Pelin, Serge Neault, Taha Azad, Caroline J. Breitbach, David F. Stojdl, Michael F. Burgess, Scott McComb, Rebecca Auer, Jean-Simon Diallo, Carolina S. Ilkow, John Cameron Bell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
oncolytic virus
T cell engager
CEA
FAP
CTLA4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1029269/full

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