Breaking the mold with RNA—a “RNAissance” of life science

Abstract In the past decade, RNA therapeutics have gone from being a promising concept to one of the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what many call a renaissance or “RNAissance” which is being fueled by advances in genetic engineering and delivery...

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Main Authors: Charles H. Jones, John R. Androsavich, Nina So, Matthew P. Jenkins, Derek MacCormack, Andrew Prigodich, Verna Welch, Jane M. True, Mikael Dolsten
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-023-00387-4
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author Charles H. Jones
John R. Androsavich
Nina So
Matthew P. Jenkins
Derek MacCormack
Andrew Prigodich
Verna Welch
Jane M. True
Mikael Dolsten
author_facet Charles H. Jones
John R. Androsavich
Nina So
Matthew P. Jenkins
Derek MacCormack
Andrew Prigodich
Verna Welch
Jane M. True
Mikael Dolsten
author_sort Charles H. Jones
collection DOAJ
description Abstract In the past decade, RNA therapeutics have gone from being a promising concept to one of the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what many call a renaissance or “RNAissance” which is being fueled by advances in genetic engineering and delivery systems to take on more ambitious development efforts. However, this renaissance is occurring at an unprecedented pace, which will require a different way of thinking if the field is to live up to its full potential. Recognizing this need, this article will provide a forward-looking perspective on the field of RNA medical products and the potential long-term innovations and policy shifts enabled by this revolutionary and game-changing technological platform.
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spelling doaj.art-29d29f5f45c04de3b82b3bce6a3a07112024-01-14T12:30:59ZengNature Portfolionpj Genomic Medicine2056-79442024-01-019111410.1038/s41525-023-00387-4Breaking the mold with RNA—a “RNAissance” of life scienceCharles H. Jones0John R. Androsavich1Nina So2Matthew P. Jenkins3Derek MacCormack4Andrew Prigodich5Verna Welch6Jane M. True7Mikael Dolsten8Pfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkPfizer, 66 Hudson Boulevard, New YorkAbstract In the past decade, RNA therapeutics have gone from being a promising concept to one of the most exciting frontiers in healthcare and pharmaceuticals. The field is now entering what many call a renaissance or “RNAissance” which is being fueled by advances in genetic engineering and delivery systems to take on more ambitious development efforts. However, this renaissance is occurring at an unprecedented pace, which will require a different way of thinking if the field is to live up to its full potential. Recognizing this need, this article will provide a forward-looking perspective on the field of RNA medical products and the potential long-term innovations and policy shifts enabled by this revolutionary and game-changing technological platform.https://doi.org/10.1038/s41525-023-00387-4
spellingShingle Charles H. Jones
John R. Androsavich
Nina So
Matthew P. Jenkins
Derek MacCormack
Andrew Prigodich
Verna Welch
Jane M. True
Mikael Dolsten
Breaking the mold with RNA—a “RNAissance” of life science
npj Genomic Medicine
title Breaking the mold with RNA—a “RNAissance” of life science
title_full Breaking the mold with RNA—a “RNAissance” of life science
title_fullStr Breaking the mold with RNA—a “RNAissance” of life science
title_full_unstemmed Breaking the mold with RNA—a “RNAissance” of life science
title_short Breaking the mold with RNA—a “RNAissance” of life science
title_sort breaking the mold with rna a rnaissance of life science
url https://doi.org/10.1038/s41525-023-00387-4
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