Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation
SARS-CoV-2 pathogenesis is very complex and not fully understood yet. Here, Jeong et al. show that intranasally infected K18-hACE2 transgenic mice develop ocular infection and retinal inflammation, while intratracheal infection results in the dissemination of SARS-CoV-2 from mouse lungs to their bra...
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Bibliographic Details
| Main Authors: |
Gi Uk Jeong,
Hyung-Jun Kwon,
Wern Hann Ng,
Xiang Liu,
Hyun Woo Moon,
Gun Young Yoon,
Hye Jin Shin,
In-Chul Lee,
Zheng Lung Ling,
Alanna G. Spiteri,
Nicholas J. C. King,
Adam Taylor,
Ji Soo Chae,
Chonsaeng Kim,
Dae-Gyun Ahn,
Kyun-Do Kim,
Young Bae Ryu,
Seong-Jun Kim,
Suresh Mahalingam,
Young-Chan Kwon |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-35225-1
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