Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article
Background: Since the outbreak of COVID-19, various treatments have been frequently reported for patients infected with this virus, especially in transplant patient recipients. Investigating o the literature and organ transplant patients with COVID-19, it could pave the way to understanding, handlin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2022-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-2573-en.html |
| _version_ | 1811272489934782464 |
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| author | Zahra Sheikhalipour Masood Faghihdinevari Hanieh Salehi-Pourmehr Maryam Khameneh Leila Vahedi |
| author_facet | Zahra Sheikhalipour Masood Faghihdinevari Hanieh Salehi-Pourmehr Maryam Khameneh Leila Vahedi |
| author_sort | Zahra Sheikhalipour |
| collection | DOAJ |
| description | Background: Since the outbreak of COVID-19, various treatments have been frequently reported for patients infected with this virus, especially in transplant patient recipients. Investigating o the literature and organ transplant patients with COVID-19, it could pave the way to understanding, handling, and treatment of COVID-19.
Methods: We had a brief review of the literature on immunosuppressive therapy in kidney transplants infected with COVID-19 based on the PubMed Database by keywords “kidney, transplant, COVID-19, and immunosuppress” after hospitalization of a kidney transplant reception infected with COVID-19. He had already been recorded in the Organ Transplant Registry (ID≠ 64510) of Tabriz University of Medical Sciences /Iran.
Results: We reported the clinical course of a 45-year-old man with a history of kidney transplant and immunotherapy who was infected with COVID-19 with respiratory infections and positive RT-PCR (Real-time polymerase chain reaction). He was treated with hydroxychloroquine, Kaletra, Cellcept, and Prednisolone for 5 days, and finally discharged from the hospital. In addition, the reviewing of 48 papers with 745 samples showed that immunosuppressant medications alone could be a therapeutic choice in kidney transplants infected with COVID-19 with careful management.
Conclusion: The patients with organ transplantation infected with COVID-19 may show different clinical signs, clinical course, and prognosis due to underlying diseases and the use of immunosuppressant medications. It might be best to continue taking the immunosuppressant medications but to modify them based on patients conditions such as clinical symptoms, laboratory results, paraclinical examinations. |
| first_indexed | 2024-04-12T22:41:14Z |
| format | Article |
| id | doaj.art-29d544d09c2e4d8b89c1e9acc2422668 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-04-12T22:41:14Z |
| publishDate | 2022-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-29d544d09c2e4d8b89c1e9acc24226682022-12-22T03:13:42ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722022-01-0113Covid 19 Supplement 2161172Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review articleZahra Sheikhalipour0Masood Faghihdinevari1Hanieh Salehi-Pourmehr2Maryam Khameneh3Leila Vahedi4 1. Medical and Surgical Department, Nursing and Midwifery School, Organ Transplant Registry, Tabriz University of Medical Sciences, Iran Liver and Gastrointestinal Diseases Research Center, Organ Transplant Registry, Tabriz University of Medical Sciences, Tabriz, Iran Research Center for Evidence-Based Medicine, Iranian EBM Centre: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran Student Research Committee, Islamic Azad University of Tabriz, Tabriz, Iran Liver and Gastrointestinal Diseases Research Center, Organ Transplant Registry, Tabriz University of Medical Sciences, Tabriz, Iran Background: Since the outbreak of COVID-19, various treatments have been frequently reported for patients infected with this virus, especially in transplant patient recipients. Investigating o the literature and organ transplant patients with COVID-19, it could pave the way to understanding, handling, and treatment of COVID-19. Methods: We had a brief review of the literature on immunosuppressive therapy in kidney transplants infected with COVID-19 based on the PubMed Database by keywords “kidney, transplant, COVID-19, and immunosuppress” after hospitalization of a kidney transplant reception infected with COVID-19. He had already been recorded in the Organ Transplant Registry (ID≠ 64510) of Tabriz University of Medical Sciences /Iran. Results: We reported the clinical course of a 45-year-old man with a history of kidney transplant and immunotherapy who was infected with COVID-19 with respiratory infections and positive RT-PCR (Real-time polymerase chain reaction). He was treated with hydroxychloroquine, Kaletra, Cellcept, and Prednisolone for 5 days, and finally discharged from the hospital. In addition, the reviewing of 48 papers with 745 samples showed that immunosuppressant medications alone could be a therapeutic choice in kidney transplants infected with COVID-19 with careful management. Conclusion: The patients with organ transplantation infected with COVID-19 may show different clinical signs, clinical course, and prognosis due to underlying diseases and the use of immunosuppressant medications. It might be best to continue taking the immunosuppressant medications but to modify them based on patients conditions such as clinical symptoms, laboratory results, paraclinical examinations.http://caspjim.com/article-1-2573-en.htmlcovid- 19kidney transplantimmunosuppressantreview |
| spellingShingle | Zahra Sheikhalipour Masood Faghihdinevari Hanieh Salehi-Pourmehr Maryam Khameneh Leila Vahedi Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article Caspian Journal of Internal Medicine covid- 19 kidney transplant immunosuppressant review |
| title | Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article |
| title_full | Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article |
| title_fullStr | Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article |
| title_full_unstemmed | Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article |
| title_short | Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article |
| title_sort | covid 19 in kidney transplant recipients with immunosuppressive therapy a case report and review article |
| topic | covid- 19 kidney transplant immunosuppressant review |
| url | http://caspjim.com/article-1-2573-en.html |
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