Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm.

Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm.

Echinoderms, which are phylogenetically related to vertebrates and produce large numbers of transparent embryos that can be experimentally manipulated, offer many advantages for the analysis of the gene regulatory networks (GRN) regulating germ layer formation. During development of the sea urchin e...

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Bibliographic Details
Main Authors: Alexandra Saudemont, Emmanuel Haillot, Flavien Mekpoh, Nathalie Bessodes, Magali Quirin, François Lapraz, Véronique Duboc, Eric Röttinger, Ryan Range, Arnaud Oisel, Lydia Besnardeau, Patrick Wincker, Thierry Lepage
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3009687?pdf=render

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