LUMINESCENCE DETERMINATION OF ETODOLAC
A highly sensitive, simple and rapid method for determination of non-steroidal anti- inflammatory drug – etodolac (Et) in washings from surfaces of pharmaceutical equipment have been proposed. The intensity of native luminescence of water-n-propanol solutions of etodolac (λex= 274 nm; λlum= 350 nm)...
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Format: | Article |
Language: | English |
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Odessa I. I. Mechnikov National University
2015-02-01
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Series: | Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
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Online Access: | http://heraldchem.onu.edu.ua/article/view/38316 |
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author | A. V. Yegorova Yu. V. Skrypynets I. I. Leonenko G. V. Anelchуk E. V. Malinka |
author_facet | A. V. Yegorova Yu. V. Skrypynets I. I. Leonenko G. V. Anelchуk E. V. Malinka |
author_sort | A. V. Yegorova |
collection | DOAJ |
description | A highly sensitive, simple and rapid method for determination of non-steroidal anti- inflammatory drug – etodolac (Et) in washings from surfaces of pharmaceutical equipment have been proposed. The intensity of native luminescence of water-n-propanol solutions of etodolac (λex= 274 nm; λlum= 350 nm) was used as the analytical signal. The calibration graph is linear in the concentration range 0.014-2.3 μg/ml, the limit of detection is 0.5 ng/ml. |
first_indexed | 2024-04-13T06:14:10Z |
format | Article |
id | doaj.art-29dfdbeb55eb463b84ca6d5bf4e97e45 |
institution | Directory Open Access Journal |
issn | 2304-0947 2414-5963 |
language | English |
last_indexed | 2024-04-13T06:14:10Z |
publishDate | 2015-02-01 |
publisher | Odessa I. I. Mechnikov National University |
record_format | Article |
series | Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
spelling | doaj.art-29dfdbeb55eb463b84ca6d5bf4e97e452022-12-22T02:58:53ZengOdessa I. I. Mechnikov National UniversityVìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ2304-09472414-59632015-02-01191(49)455110.18524/2304-0947.2014.1(49).3831638316LUMINESCENCE DETERMINATION OF ETODOLACA. V. Yegorova0Yu. V. Skrypynets1I. I. Leonenko2G. V. Anelchуk3E. V. Malinka4Фізико-хімічний інститут ім. О.В.Богатського НАН УкраїниФізико-хімічний інститут ім. О.В.Богатського НАН УкраїниФізико-хімічний інститут ім. О.В.Богатського НАН УкраїниОдеська національна академія харчових технологійОдеська національна академія харчових технологій; Фізико-хімічний інститут ім. О.В.Богатського НАН УкраїниA highly sensitive, simple and rapid method for determination of non-steroidal anti- inflammatory drug – etodolac (Et) in washings from surfaces of pharmaceutical equipment have been proposed. The intensity of native luminescence of water-n-propanol solutions of etodolac (λex= 274 nm; λlum= 350 nm) was used as the analytical signal. The calibration graph is linear in the concentration range 0.014-2.3 μg/ml, the limit of detection is 0.5 ng/ml.http://heraldchem.onu.edu.ua/article/view/38316люмінесценція, етодолак, очистка фармобладнання |
spellingShingle | A. V. Yegorova Yu. V. Skrypynets I. I. Leonenko G. V. Anelchуk E. V. Malinka LUMINESCENCE DETERMINATION OF ETODOLAC Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ люмінесценція, етодолак, очистка фармобладнання |
title | LUMINESCENCE DETERMINATION OF ETODOLAC |
title_full | LUMINESCENCE DETERMINATION OF ETODOLAC |
title_fullStr | LUMINESCENCE DETERMINATION OF ETODOLAC |
title_full_unstemmed | LUMINESCENCE DETERMINATION OF ETODOLAC |
title_short | LUMINESCENCE DETERMINATION OF ETODOLAC |
title_sort | luminescence determination of etodolac |
topic | люмінесценція, етодолак, очистка фармобладнання |
url | http://heraldchem.onu.edu.ua/article/view/38316 |
work_keys_str_mv | AT avyegorova luminescencedeterminationofetodolac AT yuvskrypynets luminescencedeterminationofetodolac AT iileonenko luminescencedeterminationofetodolac AT gvanelchuk luminescencedeterminationofetodolac AT evmalinka luminescencedeterminationofetodolac |