High-Dimensional Mass Cytometry Analysis of Embryonic Antigens and Their Signaling Pathways in Myeloid Cells from Bone Marrow Aspirates in AML Patients at Diagnosis

High-Dimensional Mass Cytometry Analysis of Embryonic Antigens and Their Signaling Pathways in Myeloid Cells from Bone Marrow Aspirates in AML Patients at Diagnosis

Background: Embryonic antigens (EA) regulate pluripotency, self-renewal, and differentiation in embryonic stem (ES) cells during their development. In adult somatic cells, EA expression is normally inhibited; however, EAs can be re-expressed by cancer cells and are involved in the deregulation of di...

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Bibliographic Details
Main Authors: Carmen-Mariana Aanei, Estelle Devêvre, Adrian Șerban, Emmanuelle Tavernier-Tardy, Denis Guyotat, Lydia Campos Catafal
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
acute myeloid leukemia
mass cytometry
OCT3/4
Nanog
SOX2
SSEA1
Online Access:https://www.mdpi.com/2072-6694/15/19/4707

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